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Mouse Monoclonal HPRT antibody [1F8D11] (STJ98137)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, ELISA
Recommended dilution: WB 1:500-1:2000; ELISA 1:10000
Recommended protocols: check protocols
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Check alternative names for the antibodyExpand
HPRT1 antibody, HPRT antibody,|HGPRT antibody|HGPRTase antibody|HPRT 1 antibody|HPRT_HUMAN antibody|HPRT1 antibody|Hypoxanthine guanine phosphoribosyltransferase antibody|Hypoxanthine phosphoribosyltransferase 1 (Lesch Nyhan syndrome) antibody|Hypoxanthine phosphoribosyltransferase 1 antibody|Hypoxanthine-guanine phosphoribosyltransferase antibody|Anti-HPRT antibody (ab10479)
SCBT cat No: sc-376559|sc-393915|sc-393901|sc-20906|sc-376938|sc-373979|sc-376922|sc-20975|sc-20904|
HPRT Monoclonal Antibody
|Catalogue No.|| |
HPRT Monoclonal Antibody detects endogenous levels of HPRT protein.
Purified recombinant fragment of HPRT expressed in E Coli
|Recommended dilution|| |
WB 1:500-1:2000; ELISA 1:10000
HPRT Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.
HPRT Antibody was purified using affinity purification.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Hypoxanthine-guanine phosphoribosyltransferase antibody, HGPRT antibody, HGPRTase antibody,
|Protein names|| |
Hypoxanthine-guanine phosphoribosyltransferase , HGPRT , HGPRTase ,
|Protein function|| |
Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5-phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway. / IMP + diphosphate = hypoxanthine + 5-phospho-alpha-D-ribose 1-diphosphate. / GMP + diphosphate = guanine + 5-phospho-alpha-D-ribose 1-diphosphate. / Mg2+ / 5.4 µM for IMP / 0.45 µM for hypoxanthine / 25 µM for pyrophosphate / 31 µM for phosphoribosylpyrophosphate /
|Involvement in disease|| |
Lesch-Nyhan syndrome (LNS) [MIM:300322]: Characterized by complete lack of enzymatic activity that results in hyperuricemia, choreoathetosis, mental retardation, and compulsive self-mutilation. . Note: The disease is caused by mutations affecting the gene represented in this entry.; Gout HPRT-related (GOUT-HPRT) [MIM:300323]: Characterized by partial enzyme activity and hyperuricemia. . Note: The disease is caused by mutations affecting the gene represented in this entry.
|Protein sequence and domain|| |
Belongs to the purine/pyrimidine phosphoribosyltransferase family.
|Protein cellular localization|| |
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St John’s Laboratory Ltd.
|Product type|| |
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