Mouse Monoclonal HPRT antibody [1F8D11] (STJ98137)

$379.00

Reactivity: Human
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Mouse Monoclonal HPRT antibody [1F8D11] (STJ98137)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-1:2000; ELISA 1:10000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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HPRT1 antibody, HPRT antibody,|HGPRT antibody|HGPRTase antibody|HPRT 1 antibody|HPRT_HUMAN antibody|HPRT1 antibody|Hypoxanthine guanine phosphoribosyltransferase antibody|Hypoxanthine phosphoribosyltransferase 1 (Lesch Nyhan syndrome) antibody|Hypoxanthine phosphoribosyltransferase 1 antibody|Hypoxanthine-guanine phosphoribosyltransferase antibody|Anti-HPRT antibody (ab10479)
SCBT cat No: sc-376559|sc-393915|sc-393901|sc-20906|sc-376938|sc-373979|sc-376922|sc-20975|sc-20904|

 

Name

HPRT Monoclonal Antibody

Catalogue No.

STJ98137

Reactivity

Human

Specificity

HPRT Monoclonal Antibody detects endogenous levels of HPRT protein.

Immunogen

Purified recombinant fragment of HPRT expressed in E Coli

Host

Mouse

Applications

WB, ELISA

Recommended dilution

WB 1:500-1:2000; ELISA 1:10000

Clonality

Monoclonal

Conjugation

Unconjugated

Isotype

IgG2b

Formulation

HPRT Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.

Concentration

1 mg/ml

Purification

HPRT Antibody was purified using affinity purification.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Hypoxanthine-guanine phosphoribosyltransferase antibody, HGPRT antibody, HGPRTase antibody,

Database links

Human UniProt/Swiss-Prot:P00492;Mouse UniPort/Swiss-Prot: P00493;Rat UniProt/Swiss-Port: P27605;Human Entrez Gene: 3251;Mouse Entrez Gene: 15452;Rat Entrez Gene: Rn.47

Protein names

Hypoxanthine-guanine phosphoribosyltransferase , HGPRT , HGPRTase ,

Protein function

Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5-phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway. / IMP + diphosphate = hypoxanthine + 5-phospho-alpha-D-ribose 1-diphosphate. / GMP + diphosphate = guanine + 5-phospho-alpha-D-ribose 1-diphosphate. / Mg2+ / 5.4 µM for IMP / 0.45 µM for hypoxanthine / 25 µM for pyrophosphate / 31 µM for phosphoribosylpyrophosphate /

Involvement in disease

Lesch-Nyhan syndrome (LNS) [MIM:300322]: Characterized by complete lack of enzymatic activity that results in hyperuricemia, choreoathetosis, mental retardation, and compulsive self-mutilation. . Note: The disease is caused by mutations affecting the gene represented in this entry.; Gout HPRT-related (GOUT-HPRT) [MIM:300323]: Characterized by partial enzyme activity and hyperuricemia. . Note: The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the purine/pyrimidine phosphoribosyltransferase family.

Protein cellular localization

Cytoplasm

Research area

All research areas>Signaling Intermediates>HPRT
(View all antibody categories related to Signaling Intermediates)

Note

AntibodyPlus can customize HPRT Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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