Mouse Monoclonal HXK I antibody [7A7] (STJ98150)

$379.00

Reactivity: Human, Mouse, Rat
Applications: WB, IHC, IF, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Mouse Monoclonal HXK I antibody [7A7] (STJ98150)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IHC, IF, ELISA

Recommended dilution: WB 1:500-1:2000; IHC 1:200-1:1000; IF 1:200-1:1000; ELISA 1:10000

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for HXK I Monoclonal Antibody.

Alternative names:

Check alternative names for the antibody

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HK1 antibody,|Brain form hexokinase antibody|Hexokinase 1 antibody|Hexokinase type I antibody|HK I antibody|HK1 ta antibody|HK1 tb antibody|HK1 tc antibody|HKI antibody|HXK1 antibody|Anti-pan-Hexokinase antibody [4D7] (ab58979)
SCBT cat No: sc-80978|sc-390517|sc-271865|sc-6518|sc-46695|sc-28885|

 

Name

HXK I Monoclonal Antibody

Catalogue No.

STJ98150

Reactivity

Human, Mouse, Rat

Specificity

HXK I Monoclonal Antibody detects endogenous levels of HXK I protein.

Immunogen

Purified recombinant fragment of human HXK I expressed in E Coli

Host

Mouse

Applications

WB, IHC, IF, ELISA

Recommended dilution

WB 1:500-1:2000; IHC 1:200-1:1000; IF 1:200-1:1000; ELISA 1:10000

Clonality

Monoclonal

Conjugation

Unconjugated

Isotype

IgG1

Formulation

HXK I Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.

Concentration

1 mg/ml

Purification

HXK I Antibody was purified using affinity purification.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Hexokinase-1 antibody, Brain form hexokinase antibody, Hexokinase type I antibody, HK I antibody

Database links

Human UniProt/Swiss-Prot:P19367;Mouse UniPort/Swiss-Prot: P17710;Rat UniProt/Swiss-Port: P05708;Human Entrez Gene: 3098;Mouse Entrez Gene: 15275;Rat Entrez Gene: Rn.11017

Protein names

Hexokinase-1 , Brain form hexokinase , Hexokinase type I , HK I

Protein function

ATP + D-hexose = ADP + D-hexose 6-phosphate. / Hexokinase is an allosteric enzyme inhibited by its product Glc-6-P. /

Protein tissue specificity

Isoform 2 is erythrocyte specific. Isoform 3 and isoform 4 are testis-specific.

Involvement in disease

Hexokinase deficiency (HK deficiency) [MIM:235700]: Rare autosomal recessive disease with nonspherocytic hemolytic anemia as the predominant clinical feature. . Note: The disease is caused by mutations affecting the gene represented in this entry.; Neuropathy, hereditary motor and sensory, Russe type (HMSNR) [MIM:605285]: An autosomal recessive progressive complex peripheral neuropathy characterized by onset in the first decade of distal lower limb weakness and muscle atrophy resulting in walking difficulties. Distal impairment of the upper limbs usually occurs later, as does proximal lower limb weakness. There is distal sensory impairment, with pes cavus and areflexia. Laboratory studies suggest that it is a myelinopathy resulting in reduced nerve conduction velocities in the demyelinating range as well as a length-dependent axonopathy. . Note: The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

The N- and C-terminal halves of this hexokinase show extensive sequence similarity to each other. The catalytic activity is associated with the C-terminus while regulatory function is associated with the N-terminus. Each domain can bind a single glucose and Gluc-6-P molecule. / Belongs to the hexokinase family. / Contains 2 hexokinase domains.

Protein cellular localization

Mitochondrion outer membrane

Research area

All research areas>Kinases and Phosphatases>HXK I
(View all antibody categories related to Kinases and Phosphatases)

Note

AntibodyPlus can customize HXK I Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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