Mouse Monoclonal IDE antibody [3H4] (STJ96985)

$99.00$319.00

Reactivity: Human
Applications: WB, IHC, IF
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Mouse Monoclonal IDE antibody [3H4] (STJ96985)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB

Recommended dilution: WB 1:1000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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IDE antibody,|Abeta-degrading protease antibody|FLJ35968 antibody|Ide antibody|IDE_HUMAN antibody|Insulin protease antibody|Insulin-degrading enzyme antibody|Insulinase antibody|Insulysin antibody|OTTHUMP00000020097 antibody|Anti-Insulin degrading enzyme / IDE antibody (ab32216)
SCBT cat No: sc-130784|sc-514458|sc-393887|sc-27266|sc-27265|

Name

IDE Monoclonal Antibody

Catalogue No.

STJ96985

Reactivity

Human

Specificity

The antibody detects endogenous IDE proteins.

Immunogen

Synthetic Peptide

Host

Mouse

Applications

WB

Recommended dilution

WB 1:1000

Clonality

Monoclonal

Conjugation

Unconjugated

Isotype

IgG1

Formulation

IDE Antibody was tube-contained. PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.

Purification

IDE Antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Insulin-degrading enzyme antibody, Abeta-degrading protease antibody, Insulin protease antibody, Insulinase antibody, Insulysin antibody

Database links

Human UniProt/Swiss-Prot:P14735;Rat UniProt/Swiss-Port: P35559;Human Entrez Gene: 3416;Mouse Entrez Gene: 15925;Rat Entrez Gene: Rn.202992

Protein names

Insulin-degrading enzyme , Abeta-degrading protease , Insulin protease , Insulinase , Insulysin

Protein function

Plays a role in the cellular breakdown of insulin, IAPP, glucagon, bradykinin, kallidin and other peptides, and thereby plays a role in intercellular peptide signaling. Degrades amyloid formed by APP and IAPP. May play a role in the degradation and clearance of naturally secreted amyloid beta-protein by neurons and microglia. / (Microbial infection) The membrane-associated isoform acts as an entry receptor for varicella-zoster virus (VZV). / Degradation of insulin, glucagon and other polypeptides. No action on proteins. / Zn2+ / Activated by small peptides (By similarity). Activated by ATP and GTP, and to a lesser extent by CTP, TTP and PPPi. Inhibited by bacitracin. Inhibited by S-nitrosylation and oxidation agents.

Protein sequence and domain

The SlyX motif may be involved in the non-conventional secretion of the protein. / Belongs to the peptidase M16 family.

Protein post-translational modifications

The N-terminus is blocked.

Protein cellular localization

Cytoplasm / Cell membrane / Secreted

Research area

All research areas>Signaling Intermediates>IDE
(View all antibody categories related to Signaling Intermediates)

Note

AntibodyPlus can customize IDE Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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Immunofluorescence analysis of Human breast tissue

1: IDE Monoclonal Antibody(3H4)(red) was diluted at 1:200 (4 degree Celsius,overnight).
2: Cy3 labled Secondary antibody was diluted at 1:300 (room temperature, 50min).
3: Picture B: DAPI(blue) 10min. Picture A:Target. Picture B: DAPI. Picture C: merge of A+B.
 

Immunofluorescence analysis of Human breast tissue

1: IDE Monoclonal Antibody(3H4)(red) was diluted at 1:200 (4 degree Celsius,overnight).
2: Cy3 labled Secondary antibody was diluted at 1:300 (room temperature, 50min).
3: Picture B: DAPI(blue) 10min. Picture A:Target. Picture B: DAPI. Picture C: merge of A+B.
 

Immunofluorescence analysis of Human liver cancer tissue

1: IDE Monoclonal Antibody(3H4)(red) was diluted at 1:200 (4 degree Celsius,overnight).
2: Cy3 labled Secondary antibody was diluted at 1:300 (room temperature, 50min).
3: Picture B: DAPI(blue) 10min. Picture A:Target. Picture B: DAPI. Picture C: merge of A+B.
 

Immunofluorescence analysis of Human liver cancer tissue

1: IDE Monoclonal Antibody(3H4)(red) was diluted at 1:200 (4 degree Celsius,overnight).
2: Cy3 labled Secondary antibody was diluted at 1:300 (room temperature, 50min).
3: Picture B: DAPI(blue) 10min. Picture A:Target. Picture B: DAPI. Picture C: merge of A+B.
 

Immunofluorescence analysis of Human liver cancer tissue

1: IDE Monoclonal Antibody(3H4)(red) was diluted at 1:200 (4 degree Celsius,overnight).
2: Cy3 labled Secondary antibody was diluted at 1:300 (room temperature, 50min).
3: Picture B: DAPI(blue) 10min. Picture A:Target. Picture B: DAPI. Picture C: merge of A+B.
 

Immunohistochemical analysis of paraffin embedded Human liver cancer tissue

1: IDE Monoclonal Antibody(3H4) was diluted at 1:200 (4 degree Celsius,overnight).
2: Sodium citrate pH 6.0 was used for antibody retrieval (>98 degree Celsius,20min).
3: Secondary antibody was diluted at 1:200 (room temperature, 30min). Negative control was used by secondary antibody only.
 

Immunohistochemical analysis of paraffin embedded Human lung cancer tissue

1: IDE Monoclonal Antibody(3H4) was diluted at 1:200 (4 degree Celsius,overnight).
2: Sodium citrate pH 6.0 was used for antibody retrieval (>98 degree Celsius,20min).
3: Secondary antibody was diluted at 1:200 (room temperature, 30min). Negative control was used by secondary antibody only.
 

Immunohistochemical analysis of paraffin embedded Human kidney tissue

1: IDE Monoclonal Antibody(3H4) was diluted at 1:200 (4 degree Celsius,overnight).
2: Sodium citrate pH 6.0 was used for antibody retrieval (>98 degree Celsius,20min).
3: Secondary antibody was diluted at 1:200 (room temperature, 30min). Negative control was used by secondary antibody only.


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