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Mouse Monoclonal IkappaB-beta antibody [7B4] (STJ98186)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, ELISA
Recommended dilution: WB 1:500-1:2000; ELISA 1:10000
Recommended protocols: check protocols
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Check alternative names for the antibodyExpand
NFKBIB antibody, IKBB antibody, TRIP9 antibody,|I kappa B beta antibody|I-kappa-B-beta antibody|IkappaBbeta antibody|IKB beta antibody|IkB-B antibody|IkB-beta antibody|IKBB antibody|IKBB_HUMAN antibody|IkBbeta antibody|NF kappa BIB antibody|NF-kappa-B inhibitor beta antibody|NF-kappa-BIB antibody|Nfkbib antibody|Thyroid receptor interacting protein 9 antibody|Thyroid receptor-interacting protein 9 antibody|TR interacting protein 9 antibody|TR-interacting protein 9 antibody|TRIP-9 antibody|TRIP9 antibody|Anti-IKB beta antibody (ab7547)
SCBT cat No: sc-74453|
IkappaB-beta Monoclonal Antibody
|Catalogue No.|| |
IkappaB-beta Monoclonal Antibody detects endogenous levels of IkappaB-beta protein.
Purified recombinant fragment of human IkappaB-beta expressed in E Coli
|Recommended dilution|| |
WB 1:500-1:2000; ELISA 1:10000
IkappaB-beta Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.
IkappaB-beta Antibody was purified using affinity purification.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
NF-kappa-B inhibitor beta antibody, NF-kappa-BIB antibody, I-kappa-B-beta antibody, IkB-B antibody, IkB-beta antibody, IkappaBbeta antibody, Thyroid receptor-interacting protein 9 antibody, TR-interacting protein 9 antibody, TRIP-9 antibody
|Protein names|| |
NF-kappa-B inhibitor beta , NF-kappa-BIB , I-kappa-B-beta , IkB-B , IkB-beta , IkappaBbeta , Thyroid receptor-interacting protein 9 , TR-interacting protein 9 , TRIP-9
|Protein function|| |
Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.
|Protein tissue specificity|| |
Expressed in all tissues examined.
|Protein sequence and domain|| |
Belongs to the NF-kappa-B inhibitor family. / Contains 6 ANK repeats.
|Protein post-translational modifications|| |
Phosphorylated by RPS6KA1; followed by degradation. Interaction with NKIRAS1 and NKIRAS2 probably prevents phosphorylation.
|Protein cellular localization|| |
Cytoplasm / Nucleus
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St John’s Laboratory Ltd.
|Product type|| |
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