Mouse Monoclonal IkappaB-beta antibody [7B4] (STJ98186)

$379.00

Reactivity: Human
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Mouse Monoclonal IkappaB-beta antibody [7B4] (STJ98186)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-1:2000; ELISA 1:10000

Recommended protocols: check protocols

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Alternative names:

Check alternative names for the antibody

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NFKBIB antibody, IKBB antibody, TRIP9 antibody,|I kappa B beta antibody|I-kappa-B-beta antibody|IkappaBbeta antibody|IKB beta antibody|IkB-B antibody|IkB-beta antibody|IKBB antibody|IKBB_HUMAN antibody|IkBbeta antibody|NF kappa BIB antibody|NF-kappa-B inhibitor beta antibody|NF-kappa-BIB antibody|Nfkbib antibody|Thyroid receptor interacting protein 9 antibody|Thyroid receptor-interacting protein 9 antibody|TR interacting protein 9 antibody|TR-interacting protein 9 antibody|TRIP-9 antibody|TRIP9 antibody|Anti-IKB beta antibody (ab7547)
SCBT cat No: sc-74453|

 

Name

IkappaB-beta Monoclonal Antibody

Catalogue No.

STJ98186

Reactivity

Human

Specificity

IkappaB-beta Monoclonal Antibody detects endogenous levels of IkappaB-beta protein.

Immunogen

Purified recombinant fragment of human IkappaB-beta expressed in E Coli

Host

Mouse

Applications

WB, ELISA

Recommended dilution

WB 1:500-1:2000; ELISA 1:10000

Clonality

Monoclonal

Conjugation

Unconjugated

Isotype

IgG1

Formulation

IkappaB-beta Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.

Concentration

1 mg/ml

Purification

IkappaB-beta Antibody was purified using affinity purification.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

NF-kappa-B inhibitor beta antibody, NF-kappa-BIB antibody, I-kappa-B-beta antibody, IkB-B antibody, IkB-beta antibody, IkappaBbeta antibody, Thyroid receptor-interacting protein 9 antibody, TR-interacting protein 9 antibody, TRIP-9 antibody

Database links

Human UniProt/Swiss-Prot:Q15653;Mouse UniPort/Swiss-Prot: Q60778;Rat UniProt/Swiss-Port: Q5U342;Human Entrez Gene: 4793;Mouse Entrez Gene: 18036;Rat Entrez Gene: Rn.8395

Protein names

NF-kappa-B inhibitor beta , NF-kappa-BIB , I-kappa-B-beta , IkB-B , IkB-beta , IkappaBbeta , Thyroid receptor-interacting protein 9 , TR-interacting protein 9 , TRIP-9

Protein function

Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.

Protein tissue specificity

Expressed in all tissues examined.

Protein sequence and domain

Belongs to the NF-kappa-B inhibitor family. / Contains 6 ANK repeats.

Protein post-translational modifications

Phosphorylated by RPS6KA1; followed by degradation. Interaction with NKIRAS1 and NKIRAS2 probably prevents phosphorylation.

Protein cellular localization

Cytoplasm / Nucleus

Research area

All research areas>Transcription Regulators>I κ B
(View all antibody categories related to Transcription Regulators)

Note

AntibodyPlus can customize IkappaB-beta Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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