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Mouse Monoclonal IL-16 antibody [5D8] (STJ98169)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, ELISA
Recommended dilution: WB 1:500-1:2000; ELISA 1:10000
Recommended protocols: check protocols
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Check alternative names for the antibodyExpand
IL16 antibody,|HGNC:5980 antibody|HsT19289 antibody|IL-16 antibody|IL16 antibody|IL16_HUMAN antibody|Interleukin 16 precursor antibody|Interleukin-16 antibody|LCF antibody|Lymphocyte chemoattractant factor antibody|Neuronal interleukin 16 antibody|NIL16 antibody|prIL 16 antibody|PrIL16 antibody|Prointerleukin 16 antibody|Anti-IL16 antibody [EPR19988] (ab207181)
SCBT cat No: sc-374606|sc-374604|sc-1941|sc-374605|sc-7902|
IL-16 Monoclonal Antibody
|Catalogue No.|| |
IL-16 Monoclonal Antibody detects endogenous levels of IL-16 protein.
Purified recombinant fragment of human IL-16 expressed in E Coli
|Recommended dilution|| |
WB 1:500-1:2000; ELISA 1:10000
IL-16 Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.
IL-16 Antibody was purified using affinity purification.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
|Protein names|| |
|Protein function|| |
Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4. / Isoform 1 may act as a scaffolding protein that anchors ion channels in the membrane. / Isoform 3 is involved in cell cycle progression in T-cells. Appears to be involved in transcriptional regulation of SKP2 and is probably part of a transcriptional repression complex on the core promoter of the SKP2 gene. May act as a scaffold for GABPB1 (the DNA-binding subunit the GABP transcription factor complex) and HDAC3 thus maintaining transcriptional repression and blocking cell cycle progression in resting T-cells.
|Protein tissue specificity|| |
Isoform 3 is expressed in hemopoietic tissues, such as resting T-cells, but is undetectable during active T-cell proliferation.
|Protein sequence and domain|| |
Contains 4 PDZ (DHR) domains.
|Protein post-translational modifications|| |
Isoform 3 is synthesized as a chemo-attractant inactive precursor in hemopoietic tissues and is proteolytically cleaved by caspase-3 to yield IL-16.
|Protein cellular localization|| |
Secreted / Cytoplasm / Cytoplasm / Nucleus
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St John’s Laboratory Ltd.
|Product type|| |
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