Mouse Monoclonal IL-16 antibody [5D8] (STJ98169)

$379.00

Reactivity: Human
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Mouse Monoclonal IL-16 antibody [5D8] (STJ98169)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-1:2000; ELISA 1:10000

Recommended protocols: check protocols

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Alternative names:

Check alternative names for the antibody

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IL16 antibody,|HGNC:5980 antibody|HsT19289 antibody|IL-16 antibody|IL16 antibody|IL16_HUMAN antibody|Interleukin 16 precursor antibody|Interleukin-16 antibody|LCF antibody|Lymphocyte chemoattractant factor antibody|Neuronal interleukin 16 antibody|NIL16 antibody|prIL 16 antibody|PrIL16 antibody|Prointerleukin 16 antibody|Anti-IL16 antibody [EPR19988] (ab207181)
SCBT cat No: sc-374606|sc-374604|sc-1941|sc-374605|sc-7902|

 

Name

IL-16 Monoclonal Antibody

Catalogue No.

STJ98169

Reactivity

Human

Specificity

IL-16 Monoclonal Antibody detects endogenous levels of IL-16 protein.

Immunogen

Purified recombinant fragment of human IL-16 expressed in E Coli

Host

Mouse

Applications

WB, ELISA

Recommended dilution

WB 1:500-1:2000; ELISA 1:10000

Clonality

Monoclonal

Conjugation

Unconjugated

Isotype

IgG1

Formulation

IL-16 Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.

Concentration

1 mg/ml

Purification

IL-16 Antibody was purified using affinity purification.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Pro-interleukin-16 antibody

Database links

Human UniProt/Swiss-Prot:Q14005;Mouse UniPort/Swiss-Prot: O54824;Rat UniProt/Swiss-Port: D4A4I9;Human Entrez Gene: 3603;Mouse Entrez Gene: 16170;Rat Entrez Gene: Rn.104665

Protein names

Pro-interleukin-16

Protein function

Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4. / Isoform 1 may act as a scaffolding protein that anchors ion channels in the membrane. / Isoform 3 is involved in cell cycle progression in T-cells. Appears to be involved in transcriptional regulation of SKP2 and is probably part of a transcriptional repression complex on the core promoter of the SKP2 gene. May act as a scaffold for GABPB1 (the DNA-binding subunit the GABP transcription factor complex) and HDAC3 thus maintaining transcriptional repression and blocking cell cycle progression in resting T-cells.

Protein tissue specificity

Isoform 3 is expressed in hemopoietic tissues, such as resting T-cells, but is undetectable during active T-cell proliferation.

Protein sequence and domain

Contains 4 PDZ (DHR) domains.

Protein post-translational modifications

Isoform 3 is synthesized as a chemo-attractant inactive precursor in hemopoietic tissues and is proteolytically cleaved by caspase-3 to yield IL-16.

Protein cellular localization

Secreted / Cytoplasm / Cytoplasm / Nucleus

Research area

All research areas>Growth Factors and Hormones>IL-16
(View all antibody categories related to Growth Factors and Hormones)

Note

AntibodyPlus can customize IL-16 Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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