Mouse Monoclonal IMP cyclohydrolase antibody (STJ98509)

$379.00

Reactivity: Human, Rabbit
Applications: WB
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Mouse Monoclonal IMP cyclohydrolase antibody (STJ98509)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB

Recommended dilution: WB 1:1000-1:2000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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ATIC antibody, PURH antibody, OK/SW-cl.86 antibody,|AICAR formyltransferase/IMP cyclohydrolase antibody|5 aminoimidazole 4 carboxamide 1 beta D ribonucleotide transformylase/inosinicase antibody|5 aminoimidazole 4 carboxamide ribonucleotide formyltransferase antibody|5 aminoimidazole 4 carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase antibody|5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase antibody|AICAR antibody|AICAR formyltransferase/IMP cyclohydrolase bifunctional enzyme antibody|AICAR transformylase antibody|AICARFT antibody|AICARFT/IMPCHASE antibody|ATIC antibody|Bifunctional purine biosynthesis protein PURH antibody|epididymis secretory sperm binding protein Li 70p antibody|FLJ93545 antibody|HEL-S-70p antibody|IMP cyclohydrolase antibody|IMP synthase antibody|IMP synthetase antibody|IMPCHASE antibody|Inosinicase antibody|OK/SW-cl.86 antibody|Phosphoribosylaminoimidazolecarboxamide formyltransferase antibody|Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase antibody|PUR9_HUMAN antibody|PURH antibody|Anti-ATIC antibody [F38 P7 H9] (ab33520)
SCBT cat No: sc-53612|sc-365402|

 

Name

IMP cyclohydrolase Monoclonal Antibody

Catalogue No.

STJ98509

Reactivity

Human, Rabbit

Specificity

IMP cyclohydrolase Monoclonal Antibody detects endogenous levels of IMP cyclohydrolase protein.

Immunogen

Purified recombinant human IMP cyclohydrolase protein fragments expressed in Ecoli

Host

Mouse

Applications

WB

Recommended dilution

WB 1:1000-1:2000

Clonality

Monoclonal

Conjugation

Unconjugated

Formulation

IMP cyclohydrolase Antibody was tube-contained. Purified in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol.

Concentration

1 mg/ml

Purification

IMP cyclohydrolase Antibody was purified using affinity purification.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Bifunctional purine biosynthesis protein PURH antibody

Database links

Human UniProt/Swiss-Prot:P31939;Mouse UniPort/Swiss-Prot: Q9CWJ9;Rat UniProt/Swiss-Port: O35567;Human Entrez Gene: 471;Mouse Entrez Gene: 108147;Rat Entrez Gene: Rn.15114

Protein names

Bifunctional purine biosynthesis protein PURH

Protein function

Bifunctional enzyme that catalyzes 2 steps in purine biosynthesis. / Promotes insulin receptor/INSR autophosphorylation and is involved in INSR internalization . / 10-formyltetrahydrofolate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide = tetrahydrofolate + 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide. / IMP + H2O = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide. / /

Involvement in disease

AICAR transformylase/IMP cyclohydrolase deficiency (AICAR) [MIM:608688]: A neurologically devastating inborn error of purine biosynthesis. Patients excrete massive amounts of AICA-riboside in the urine and accumulate AICA-ribotide and its derivatives in erythrocytes and fibroblasts. AICAR causes profound mental retardation, epilepsy, dysmorphic features and congenital blindness. . Note: The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

The IMP cyclohydrolase activity resides in the N-terminal region. / Belongs to the PurH family.

Research area

All research areas>Synthesis and Degradation>AICAR
(View all antibody categories related to Synthesis and Degradation)

Note

AntibodyPlus can customize IMP cyclohydrolase Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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