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Mouse Monoclonal IMP cyclohydrolase antibody (STJ98509)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB
Recommended dilution: WB 1:1000-1:2000
Recommended protocols: check protocols
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Check alternative names for the antibodyExpand
ATIC antibody, PURH antibody, OK/SW-cl.86 antibody,|AICAR formyltransferase/IMP cyclohydrolase antibody|5 aminoimidazole 4 carboxamide 1 beta D ribonucleotide transformylase/inosinicase antibody|5 aminoimidazole 4 carboxamide ribonucleotide formyltransferase antibody|5 aminoimidazole 4 carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase antibody|5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase antibody|AICAR antibody|AICAR formyltransferase/IMP cyclohydrolase bifunctional enzyme antibody|AICAR transformylase antibody|AICARFT antibody|AICARFT/IMPCHASE antibody|ATIC antibody|Bifunctional purine biosynthesis protein PURH antibody|epididymis secretory sperm binding protein Li 70p antibody|FLJ93545 antibody|HEL-S-70p antibody|IMP cyclohydrolase antibody|IMP synthase antibody|IMP synthetase antibody|IMPCHASE antibody|Inosinicase antibody|OK/SW-cl.86 antibody|Phosphoribosylaminoimidazolecarboxamide formyltransferase antibody|Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase antibody|PUR9_HUMAN antibody|PURH antibody|Anti-ATIC antibody [F38 P7 H9] (ab33520)
SCBT cat No: sc-53612|sc-365402|
IMP cyclohydrolase Monoclonal Antibody
|Catalogue No.|| |
IMP cyclohydrolase Monoclonal Antibody detects endogenous levels of IMP cyclohydrolase protein.
Purified recombinant human IMP cyclohydrolase protein fragments expressed in Ecoli
|Recommended dilution|| |
IMP cyclohydrolase Antibody was tube-contained. Purified in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol.
IMP cyclohydrolase Antibody was purified using affinity purification.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Bifunctional purine biosynthesis protein PURH antibody
|Protein names|| |
Bifunctional purine biosynthesis protein PURH
|Protein function|| |
Bifunctional enzyme that catalyzes 2 steps in purine biosynthesis. / Promotes insulin receptor/INSR autophosphorylation and is involved in INSR internalization . / 10-formyltetrahydrofolate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide = tetrahydrofolate + 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide. / IMP + H2O = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide. / /
|Involvement in disease|| |
AICAR transformylase/IMP cyclohydrolase deficiency (AICAR) [MIM:608688]: A neurologically devastating inborn error of purine biosynthesis. Patients excrete massive amounts of AICA-riboside in the urine and accumulate AICA-ribotide and its derivatives in erythrocytes and fibroblasts. AICAR causes profound mental retardation, epilepsy, dysmorphic features and congenital blindness. . Note: The disease is caused by mutations affecting the gene represented in this entry.
|Protein sequence and domain|| |
The IMP cyclohydrolase activity resides in the N-terminal region. / Belongs to the PurH family.
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St John’s Laboratory Ltd.
|Product type|| |
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