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Mouse Monoclonal Inhibin alpha antibody [4A2] (STJ98179)
Supplier: St John’s Laboratory Ltd.
Recommended applications: IHC, IF, ELISA
Recommended dilution: IHC 1:200-1:1000; IF 1:200-1:1000; ELISA 1:10000
Recommended protocols: check protocols
Click or hover above images to see image description for Inhibin alpha Monoclonal Antibody.
Check alternative names for the antibodyExpand
INHA antibody,|A inhibin subunit antibody|A inhibin subunit precursor antibody|AW55578 antibody|IHA antibody|inhA antibody|INHA_HUMAN antibody|Inhibin alpha chain antibody|Inhibin alpha chain precursor antibody|Inhibin alpha subunit antibody|Anti-Inhibin alpha antibody [R1] (ab14087)
SCBT cat No: sc-365439|sc-22047|sc-30146|sc-22048|
Inhibin alpha Monoclonal Antibody
|Catalogue No.|| |
Inhibin alpha Monoclonal Antibody detects endogenous levels of Inhibin alpha protein.
Purified recombinant fragment of human Inhibin alpha expressed in E Coli
IHC, IF, ELISA
|Recommended dilution|| |
IHC 1:200-1:1000; IF 1:200-1:1000; ELISA 1:10000
Inhibin alpha Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.
Inhibin alpha Antibody was purified using affinity purification.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Inhibin alpha chain antibody
|Protein names|| |
Inhibin alpha chain
|Protein function|| |
Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
|Protein tissue specificity|| |
Originally found in ovary (granulosa cells) and testis (Sertoli cells), but widely distributed in many tissues including brain and placenta. In adrenal cortex expression is limited to the zona reticularis and the innermost zona fasciculata in the normal gland, extending centripetally into the zona fasciculata in hyperplasia. Also found in adrenocortical tumors. Also expressed in prostate epithelium of benign prostatic hyperplasia, in regions of basal cell hyperplasia and in nonmalignant regions of high grade prostate cancer. Only circulating inhibin B is found in male, whereas circulating inhibins A and B are found in female.
|Protein sequence and domain|| |
Belongs to the TGF-beta family.
|Protein post-translational modifications|| |
Proteolytic processing yields a number of bioactive forms. The 20/23 kDa forms consist solely of the mature alpha chain, the 26/29 kDa forms consist of the most N-terminal propeptide linked through a disulfide bond to the mature alpha chain, the 50/53 kDa forms encompass the entire proprotein. Each type can be furthermore either mono- or diglycosylated, causing the mass difference.
|Protein cellular localization|| |
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St John’s Laboratory Ltd.
|Product type|| |
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