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Mouse Monoclonal LAL antibody [9G7F12; 7G6D7] (STJ98212)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, ELISA
Recommended dilution: WB 1:500-1:2000; ELISA 1:10000
Recommended protocols: check protocols
Click or hover above images to see image description for LAL Monoclonal Antibody.
Check alternative names for the antibodyExpand
LIPA antibody,|Acid cholesteryl ester hydrolase antibody|CESD antibody|cholesterol ester hydrolase antibody|cholesterol ester storage disease antibody|Cholesteryl esterase antibody|Hydrolase deficiency antibody|LAL antibody|LAL deficiency cholesterol ester antibody|LICH_HUMAN antibody|lipA antibody|LIPA deficiency antibody|Lipase A antibody|lipase A, lysosomal acid, cholesterol esterase antibody|lysosomal acid lipase antibody|lysosomal acid lipase deficiency antibody|Lysosomal acid lipase/cholesteryl ester hydrolase antibody|Sterol esterase antibody|Anti-Lysosomal acid lipase antibody (ab73445)
SCBT cat No: sc-58374|
LAL Monoclonal Antibody
|Catalogue No.|| |
LAL Monoclonal Antibody detects endogenous levels of LAL protein.
Purified recombinant fragment of LAL expressed in E Coli
|Recommended dilution|| |
WB 1:500-1:2000; ELISA 1:10000
LAL Antibody was tube-contained. Purified antibody in PBS containing 0.03% sodium azide.
LAL Antibody was purified using affinity purification.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Lysosomal acid lipase/cholesteryl ester hydrolase antibody, Acid cholesteryl ester hydrolase antibody, LAL antibody, Cholesteryl esterase antibody, Lipase A antibody, Sterol esterase antibody
|Protein names|| |
Lysosomal acid lipase/cholesteryl ester hydrolase , Acid cholesteryl ester hydrolase , LAL , Cholesteryl esterase , Lipase A , Sterol esterase
|Protein function|| |
Crucial for the intracellular hydrolysis of cholesteryl esters and triglycerides that have been internalized via receptor-mediated endocytosis of lipoprotein particles. Important in mediating the effect of LDL (low density lipoprotein) uptake on suppression of hydroxymethylglutaryl-CoA reductase and activation of endogenous cellular cholesteryl ester formation. / A steryl ester + H2O = a sterol + a fatty acid.
|Involvement in disease|| |
Wolman disease (WOD) [MIM:278000]: A severe manifestation of LIPA deficiency, leading to the accumulation of cholesteryl esters and triglycerides in most tissues of the body. WD occurs in infancy and is nearly always fatal before the age of 1 year. . Note: The disease is caused by mutations affecting the gene represented in this entry.; Cholesteryl ester storage disease (CESD) [MIM:278000]: A mild manifestation of LIPA deficiency, leading to the accumulation of cholesteryl esters and triglycerides in most tissues of the body. It is characterized by late-onset. . Note: The disease is caused by mutations affecting the gene represented in this entry.
|Protein sequence and domain|| |
Belongs to the AB hydrolase superfamily. Lipase family.
|Protein cellular localization|| |
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St John’s Laboratory Ltd.
|Product type|| |
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