Mouse Monoclonal Laminin beta-1 antibody [2D9G5] (STJ98214)

$379.00

Reactivity: Human
Applications: WB, IHC, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Mouse Monoclonal Laminin beta-1 antibody [2D9G5] (STJ98214)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IHC, ELISA

Recommended dilution: WB 1:500-1:2000; IHC 1:200-1:1000; ELISA 1:10000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

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LAMB1 antibody,|CLM antibody|Cutis laxa with marfanoid phenotype antibody|LAM B1 antibody|LAMB 1 antibody|LAMB1 antibody|LAMB1_HUMAN antibody|Laminin B1 antibody|Laminin B1 chain antibody|Laminin beta 1 chain antibody|Laminin beta 1 chain precursor antibody|Laminin beta1 antibody|Laminin subunit beta 1 antibody|Laminin subunit beta-1 antibody|Laminin-1 subunit beta antibody|Laminin-10 subunit beta antibody|Laminin-12 subunit beta antibody|Laminin-2 subunit beta antibody|Laminin-6 subunit beta antibody|Laminin-8 subunit beta antibody|LIS5 antibody|MGC142015 antibody|Anti-Laminin beta 1 antibody [LT3] (ab44941)
SCBT cat No: sc-65644|sc-17810|sc-6018|sc-17763|sc-5583|sc-33709|

 

Name

Laminin beta-1 Monoclonal Antibody

Catalogue No.

STJ98214

Reactivity

Human

Specificity

Laminin beta-1 Monoclonal Antibody detects endogenous levels of Laminin beta-1 protein.

Immunogen

Purified recombinant fragment of Laminin beta-1 (aa31-270) expressed in E Coli

Host

Mouse

Applications

WB, IHC, ELISA

Recommended dilution

WB 1:500-1:2000; IHC 1:200-1:1000; ELISA 1:10000

Clonality

Monoclonal

Conjugation

Unconjugated

Isotype

IgG2a

Formulation

Laminin beta-1 Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.

Concentration

1 mg/ml

Purification

Laminin beta-1 Antibody was purified using affinity purification.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Laminin subunit beta-1 antibody, Laminin B1 chain antibody, Laminin-1 subunit beta antibody, Laminin-10 subunit beta antibody, Laminin-12 subunit beta antibody, Laminin-2 subunit beta antibody, Laminin-6 subunit beta antibody, Laminin-8 subunit beta antibody

Database links

Human UniProt/Swiss-Prot:P07942;Mouse UniPort/Swiss-Prot: P02469;Human Entrez Gene: 3912;Mouse Entrez Gene: 16777;

Protein names

Laminin subunit beta-1 , Laminin B1 chain , Laminin-1 subunit beta , Laminin-10 subunit beta , Laminin-12 subunit beta , Laminin-2 subunit beta , Laminin-6 subunit beta , Laminin-8 subunit beta

Protein function

Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Involved in the organization of the laminar architecture of cerebral cortex. It is probably required for the integrity of the basement membrane/glia limitans that serves as an anchor point for the endfeet of radial glial cells and as a physical barrier to migrating neurons. Radial glial cells play a central role in cerebral cortical development, where they act both as the proliferative unit of the cerebral cortex and a scaffold for neurons migrating toward the pial surface.

Involvement in disease

Lissencephaly 5 (LIS5) [MIM:615191]: An autosomal recessive brain malformation characterized by cobblestone changes in the cortex, more severe in the posterior region, and subcortical band heterotopia. Affected individuals have hydrocephalus, seizures, and severely delayed psychomotor development. . Note: The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

The alpha-helical domains I and II are thought to interact with other laminin chains to form a coiled coil structure. / Domains VI and IV are globular. / Contains 13 laminin EGF-like domains. / Contains 1 laminin IV type B domain. / Contains 1 laminin N-terminal domain.

Protein cellular localization

Secreted > extracellular space > extracellular matrix > basement membrane

Research area

All research areas>Cell Adhesion Proteins>Laminin
(View all antibody categories related to Cell Adhesion Proteins)

Note

AntibodyPlus can customize Laminin beta-1 Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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