Mouse Monoclonal M-CSF antibody [2D10] (STJ98234)

$379.00

Reactivity: Human
Applications: WB, IHC, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Mouse Monoclonal M-CSF antibody [2D10] (STJ98234)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IHC, ELISA

Recommended dilution: WB 1:500-1:2000; IHC 1:200-1:1000; ELISA 1:10000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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CSF1 antibody,|Colony stimulating factor 1 (macrophage) antibody|Colony stimulating factor 1 antibody|Colony stimulating factor macrophage specific antibody|CSF 1 antibody|CSF-1 antibody|CSF1 antibody|CSF1_HUMAN antibody|Csfm antibody|Lanimostim antibody|M CSF antibody|M-CSF antibody|Macrophage Colony Stimulating Factor 1 antibody|Macrophage colony stimulating factor antibody|MCSF antibody|MGC31930 antibody|Processed macrophage colony-stimulating factor 1 antibody|Anti-M-CSF antibody (ab9693)
SCBT cat No: sc-365779|sc-13103|sc-1326|

 

Name

M-CSF Monoclonal Antibody

Catalogue No.

STJ98234

Reactivity

Human

Specificity

M-CSF Monoclonal Antibody detects endogenous levels of M-CSF protein.

Immunogen

Purified recombinant fragment of human M-CSF expressed in E Coli

Host

Mouse

Applications

WB, IHC, ELISA

Recommended dilution

WB 1:500-1:2000; IHC 1:200-1:1000; ELISA 1:10000

Clonality

Monoclonal

Conjugation

Unconjugated

Isotype

IgG1

Formulation

M-CSF Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.

Concentration

1 mg/ml

Purification

M-CSF Antibody was purified using affinity purification.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Macrophage colony-stimulating factor 1 antibody, CSF-1 antibody, M-CSF antibody, MCSF antibody, Lanimostim antibody

Database links

Human UniProt/Swiss-Prot:P09603;Mouse UniPort/Swiss-Prot: P07141;Rat UniProt/Swiss-Port: Q6GMN4;Human Entrez Gene: 1435;Mouse Entrez Gene: 12977;Rat Entrez Gene: Rn.83632

Protein names

Macrophage colony-stimulating factor 1 , CSF-1 , M-CSF , MCSF , Lanimostim

Protein function

Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female fertility. Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. Plays a role in lipoprotein clearance.

Involvement in disease

Note: Aberrant expression of CSF1 or CSF1R can promote cancer cell proliferation, invasion and formation of metastases. Overexpression of CSF1 or CSF1R is observed in a significant percentage of breast, ovarian, prostate, and endometrial cancers.; Note: Aberrant expression of CSF1 or CSF1R may play a role in inflammatory diseases, such as rheumatoid arthritis, glomerulonephritis, atherosclerosis, and allograft rejection.

Protein post-translational modifications

N- and O-glycosylated. Glycosylation and proteolytic cleavage yield different soluble forms. One high molecular weight soluble form is a proteoglycan containing chondroitin sulfate. O-glycosylated with core 1 or possibly core 8 glycans. Isoform 1 is N- and O-glycosylated. Isoform 3 is only N-glycosylated.

Protein cellular localization

Cell membrane / Single-pass type I membrane protein / Secreted > extracellular space

Research area

All research areas>Growth Factors and Hormones>M-CSF
(View all antibody categories related to Growth Factors and Hormones)

Note

AntibodyPlus can customize M-CSF Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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