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Mouse Monoclonal M-CSF antibody [2D10] (STJ98234)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, IHC, ELISA
Recommended dilution: WB 1:500-1:2000; IHC 1:200-1:1000; ELISA 1:10000
Recommended protocols: check protocols
Click or hover above images to see image description for M-CSF Monoclonal Antibody.
Check alternative names for the antibodyExpand
CSF1 antibody,|Colony stimulating factor 1 (macrophage) antibody|Colony stimulating factor 1 antibody|Colony stimulating factor macrophage specific antibody|CSF 1 antibody|CSF-1 antibody|CSF1 antibody|CSF1_HUMAN antibody|Csfm antibody|Lanimostim antibody|M CSF antibody|M-CSF antibody|Macrophage Colony Stimulating Factor 1 antibody|Macrophage colony stimulating factor antibody|MCSF antibody|MGC31930 antibody|Processed macrophage colony-stimulating factor 1 antibody|Anti-M-CSF antibody (ab9693)
SCBT cat No: sc-365779|sc-13103|sc-1326|
M-CSF Monoclonal Antibody
|Catalogue No.|| |
M-CSF Monoclonal Antibody detects endogenous levels of M-CSF protein.
Purified recombinant fragment of human M-CSF expressed in E Coli
WB, IHC, ELISA
|Recommended dilution|| |
WB 1:500-1:2000; IHC 1:200-1:1000; ELISA 1:10000
M-CSF Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.
M-CSF Antibody was purified using affinity purification.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Macrophage colony-stimulating factor 1 antibody, CSF-1 antibody, M-CSF antibody, MCSF antibody, Lanimostim antibody
|Protein names|| |
Macrophage colony-stimulating factor 1 , CSF-1 , M-CSF , MCSF , Lanimostim
|Protein function|| |
Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female fertility. Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. Plays a role in lipoprotein clearance.
|Involvement in disease|| |
Note: Aberrant expression of CSF1 or CSF1R can promote cancer cell proliferation, invasion and formation of metastases. Overexpression of CSF1 or CSF1R is observed in a significant percentage of breast, ovarian, prostate, and endometrial cancers.; Note: Aberrant expression of CSF1 or CSF1R may play a role in inflammatory diseases, such as rheumatoid arthritis, glomerulonephritis, atherosclerosis, and allograft rejection.
|Protein post-translational modifications|| |
N- and O-glycosylated. Glycosylation and proteolytic cleavage yield different soluble forms. One high molecular weight soluble form is a proteoglycan containing chondroitin sulfate. O-glycosylated with core 1 or possibly core 8 glycans. Isoform 1 is N- and O-glycosylated. Isoform 3 is only N-glycosylated.
|Protein cellular localization|| |
Cell membrane / Single-pass type I membrane protein / Secreted > extracellular space
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St John’s Laboratory Ltd.
|Product type|| |
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