Mouse Monoclonal Msx-1 antibody [5D11] (STJ98255)

$379.00

Reactivity: Human
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Mouse Monoclonal Msx-1 antibody [5D11] (STJ98255)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-1:2000; ELISA 1:10000

Recommended protocols: check protocols

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Alternative names:

Check alternative names for the antibody

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MSX1 antibody, HOX7 antibody,|AA675338 antibody|AI324650 antibody|Homeobox 7 antibody|Homeobox protein Hox-7 antibody|Homeobox protein MSX 1 antibody|Homeobox protein MSX-1 antibody|Homeobox protein MSX1 antibody|Homeobox, msh like 1 antibody|Homeobox, msh-like 1 antibody|HOX 7 antibody|Hox 7.1 antibody|Hox-7 antibody|HOX7 antibody|Hox7.1 antibody|HYD 1 antibody|HYD1 antibody|msh (Drosophila) homeo box homolog 1 (formerly homeo box 7) antibody|Msh antibody|msh homeo box 1 antibody|msh homeo box homolog 1 antibody|Msh homeobox 1 antibody|Msh homeobox 1 like protein antibody|Msh homeobox 1-like protein antibody|msh homeobox homolog 1 (Drosophila) antibody|msh homeobox homolog 1 antibody|MSH, Drosophila, Homolog of, 1 antibody|MSX 1 antibody|MSX1 antibody|MSX1_HUMAN antibody|Muscle segment homeobox antibody|Muscle segment homeobox, Drosophila, Homolog of, 1 antibody|OFC5 antibody|OTTHUMP00000115387 antibody|STHAG1 antibody|Anti-MSX1 antibody (ab174207)
SCBT cat No: sc-15395|

 

Name

Msx-1 Monoclonal Antibody

Catalogue No.

STJ98255

Reactivity

Human

Specificity

Msx-1 Monoclonal Antibody detects endogenous levels of Msx-1 protein.

Immunogen

Purified recombinant fragment of human Msx-1 expressed in E Coli

Host

Mouse

Applications

WB, ELISA

Recommended dilution

WB 1:500-1:2000; ELISA 1:10000

Clonality

Monoclonal

Conjugation

Unconjugated

Isotype

IgG1

Formulation

Msx-1 Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.

Concentration

1 mg/ml

Purification

Msx-1 Antibody was purified using affinity purification.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Homeobox protein MSX-1 antibody, Homeobox protein Hox-7 antibody, Msh homeobox 1-like protein antibody

Database links

Human UniProt/Swiss-Prot:P28360;Mouse UniPort/Swiss-Prot: P13297;Rat UniProt/Swiss-Port: Q9QUG0;Human Entrez Gene: 4487;Mouse Entrez Gene: 17701;Rat Entrez Gene: Rn.18117

Protein names

Homeobox protein MSX-1 , Homeobox protein Hox-7 , Msh homeobox 1-like protein

Protein function

Acts as a transcriptional repressor. May play a role in limb-pattern formation. Acts in cranofacial development and specifically in odontogenesis. Expression in the developing nail bed mesenchyme is important for nail plate thickness and integrity.

Protein tissue specificity

Expressed in the developing nail bed mesenchyme.

Involvement in disease

Tooth agenesis selective 1 (STHAG1) [MIM:106600]: A form of selective tooth agenesis, a common anomaly characterized by the congenital absence of one or more teeth. Selective tooth agenesis without associated systemic disorders has sometimes been divided into 2 types: oligodontia, defined as agenesis of 6 or more permanent teeth, and hypodontia, defined as agenesis of less than 6 teeth. The number in both cases does not include absence of third molars (wisdom teeth). Tooth agenesis selective type 1 can be associated with orofacial cleft in some patients. . Note: The disease is caused by mutations affecting the gene represented in this entry.; Note: MSX1 is deleted in some patients with Wolf-Hirschhorn syndrome (WHS). WHS results from sub-telomeric deletions in the short arm of chromosome 4. .; Ectodermal dysplasia 3, Witkop type (ECTD3) [MIM:189500]: A form of ectodermal dysplasia, a heterogeneous group of disorders due to abnormal development of two or more ectodermal structures such as hair, teeth, nails and sweat glands, with or without any additional clinical sign. Each combination of clinical features represents a different type of ectodermal dysplasia. ECTD3 is characterized by abnormalities largely limited largely to teeth (some of which are missing) and nails (which are poorly formed early in life, especially toenails). This condition is distinguished from anhidrotic ectodermal dysplasia by autosomal dominant inheritance and little involvement of hair and sweat glands. The teeth are not as severely affected. . Note: The disease is caused by mutations affecting the gene represented in this entry.; Non-syndromic orofacial cleft 5 (OFC5) [MIM:608874]: A birth defect consisting of cleft lips with or without cleft palate. Cleft lips are associated with cleft palate in two-third of cases. A cleft lip can occur on one or both sides and range in severity from a simple notch in the upper lip to a complete opening in the lip extending into the floor of the nostril and involving the upper gum. . Note: The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the Msh homeobox family. / Contains 1 homeobox DNA-binding domain.

Protein post-translational modifications

Sumoylated by PIAS1, desumoylated by SENP1.

Protein cellular localization

Nucleus

Research area

All research areas>Homeodomain Proteins>Msx-1
(View all antibody categories related to Homeodomain Proteins)

Note

AntibodyPlus can customize Msx-1 Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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