Mouse Monoclonal MTDH antibody [2F11C3] (STJ98256)

$379.00

Reactivity: Human
Applications: WB, IHC, FC, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Mouse Monoclonal MTDH antibody [2F11C3] (STJ98256)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IHC, FC, ELISA

Recommended dilution: WB 1:500-1:2000; IHC 1:200-1:1000; FC 1:200-1:400; ELISA 1:10000

Recommended protocols: check protocols

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Alternative names:

Check alternative names for the antibody

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MTDH antibody, AEG1 antibody, LYRIC antibody,|3D3 antibody|3D3/LYRIC antibody|AEG 1 antibody|AEG-1 antibody|AEG1 antibody|Astrocyte elevated gene 1 antibody|Astrocyte elevated gene-1 protein antibody|LYRIC antibody|LYRIC/3D3 antibody|LYRIC_HUMAN antibody|Lysine rich CEACAM1 associated protein antibody|Lysine rich CEACAM1 co isolated protein antibody|Lysine-rich CEACAM1 co-isolated protein antibody|Metadherin antibody|Metastasis adhesion protein antibody|MTDH antibody|Protein LYRIC antibody|Anti-LYRIC antibody (ab45338)
SCBT cat No: sc-517220|

 

Name

MTDH Monoclonal Antibody

Catalogue No.

STJ98256

Reactivity

Human

Specificity

MTDH Monoclonal Antibody detects endogenous levels of MTDH protein.

Immunogen

Purified recombinant fragment of human MTDH expressed in E Coli

Host

Mouse

Applications

WB, IHC, FC, ELISA

Recommended dilution

WB 1:500-1:2000; IHC 1:200-1:1000; FC 1:200-1:400; ELISA 1:10000

Clonality

Monoclonal

Conjugation

Unconjugated

Isotype

IgG1

Formulation

MTDH Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.

Concentration

1 mg/ml

Purification

MTDH Antibody was purified using affinity purification.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Protein LYRIC antibody, 3D3/LYRIC antibody, Astrocyte elevated gene-1 protein antibody, AEG-1 antibody, Lysine-rich CEACAM1 co-isolated protein antibody, Metadherin antibody, Metastasis adhesion protein antibody

Database links

Human UniProt/Swiss-Prot:Q86UE4;Mouse UniPort/Swiss-Prot: Q80WJ7;Rat UniProt/Swiss-Port: Q9Z1W6;Human Entrez Gene: 92140;Mouse Entrez Gene: 67154;Rat Entrez Gene: Rn.6864

Protein names

Protein LYRIC , 3D3/LYRIC , Astrocyte elevated gene-1 protein , AEG-1 , Lysine-rich CEACAM1 co-isolated protein , Metadherin , Metastasis adhesion protein

Protein function

Downregulates SLC1A2/EAAT2 promoter activity when expressed ectopically. Activates the nuclear factor kappa-B (NF-kappa-B) transcription factor. Promotes anchorage-independent growth of immortalized melanocytes and astrocytes which is a key component in tumor cell expansion. Promotes lung metastasis and also has an effect on bone and brain metastasis, possibly by enhancing the seeding of tumor cells to the target organ endothelium. Induces chemoresistance.

Protein tissue specificity

Widely expressed with highest levels in muscle-dominating organs such as skeletal muscle, heart, tongue and small intestine and in endocrine glands such as thyroid and adrenal gland. Overexpressed in various cancers including breast, brain, prostate, melanoma and glioblastoma multiforme.

Protein cellular localization

Endoplasmic reticulum membrane; Single-pass membrane protein / Nucleus membrane / Cell junction > tight junction / Nucleus > nucleolus / Cytoplasm > perinuclear region

Research area

All research areas>Tumor Suppressor/Apoptosis>MTDH
(View all antibody categories related to Tumor Suppressor/Apoptosis)

Note

AntibodyPlus can customize MTDH Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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