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Mouse Monoclonal MTDH antibody [2F11C3] (STJ98256)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, IHC, FC, ELISA
Recommended dilution: WB 1:500-1:2000; IHC 1:200-1:1000; FC 1:200-1:400; ELISA 1:10000
Recommended protocols: check protocols
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Check alternative names for the antibodyExpand
MTDH antibody, AEG1 antibody, LYRIC antibody,|3D3 antibody|3D3/LYRIC antibody|AEG 1 antibody|AEG-1 antibody|AEG1 antibody|Astrocyte elevated gene 1 antibody|Astrocyte elevated gene-1 protein antibody|LYRIC antibody|LYRIC/3D3 antibody|LYRIC_HUMAN antibody|Lysine rich CEACAM1 associated protein antibody|Lysine rich CEACAM1 co isolated protein antibody|Lysine-rich CEACAM1 co-isolated protein antibody|Metadherin antibody|Metastasis adhesion protein antibody|MTDH antibody|Protein LYRIC antibody|Anti-LYRIC antibody (ab45338)
SCBT cat No: sc-517220|
MTDH Monoclonal Antibody
|Catalogue No.|| |
MTDH Monoclonal Antibody detects endogenous levels of MTDH protein.
Purified recombinant fragment of human MTDH expressed in E Coli
WB, IHC, FC, ELISA
|Recommended dilution|| |
WB 1:500-1:2000; IHC 1:200-1:1000; FC 1:200-1:400; ELISA 1:10000
MTDH Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.
MTDH Antibody was purified using affinity purification.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Protein LYRIC antibody, 3D3/LYRIC antibody, Astrocyte elevated gene-1 protein antibody, AEG-1 antibody, Lysine-rich CEACAM1 co-isolated protein antibody, Metadherin antibody, Metastasis adhesion protein antibody
|Protein names|| |
Protein LYRIC , 3D3/LYRIC , Astrocyte elevated gene-1 protein , AEG-1 , Lysine-rich CEACAM1 co-isolated protein , Metadherin , Metastasis adhesion protein
|Protein function|| |
Downregulates SLC1A2/EAAT2 promoter activity when expressed ectopically. Activates the nuclear factor kappa-B (NF-kappa-B) transcription factor. Promotes anchorage-independent growth of immortalized melanocytes and astrocytes which is a key component in tumor cell expansion. Promotes lung metastasis and also has an effect on bone and brain metastasis, possibly by enhancing the seeding of tumor cells to the target organ endothelium. Induces chemoresistance.
|Protein tissue specificity|| |
Widely expressed with highest levels in muscle-dominating organs such as skeletal muscle, heart, tongue and small intestine and in endocrine glands such as thyroid and adrenal gland. Overexpressed in various cancers including breast, brain, prostate, melanoma and glioblastoma multiforme.
|Protein cellular localization|| |
Endoplasmic reticulum membrane; Single-pass membrane protein / Nucleus membrane / Cell junction > tight junction / Nucleus > nucleolus / Cytoplasm > perinuclear region
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St John’s Laboratory Ltd.
|Product type|| |
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