Mouse Monoclonal MTHFR antibody [5D3] (STJ98257)

$379.00

Reactivity: Human, Rat
Applications: WB, IHC, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Mouse Monoclonal MTHFR antibody [5D3] (STJ98257)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IHC, ELISA

Recommended dilution: WB 1:500-1:2000; IHC 1:200-1:1000; ELISA 1:10000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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MTHFR antibody,|5 10 methylenetetrahydrofolate reductase (NADPH) antibody|5 10 methylenetetrahydrofolate reductase antibody|Methylenetetrahydrofolate reductase (NAD(P)H) antibody|Methylenetetrahydrofolate reductase antibody|Methylenetetrahydrofolate reductase intermediate form antibody|MTHFR antibody|MTHR_HUMAN antibody|Anti-MTHFR antibody (ab55530)
SCBT cat No: sc-517229|sc-368720|sc-17079|

 

Name

MTHFR Monoclonal Antibody

Catalogue No.

STJ98257

Reactivity

Human, Rat

Specificity

MTHFR Monoclonal Antibody detects endogenous levels of MTHFR protein.

Immunogen

Purified recombinant fragment of human MTHFR expressed in E Coli

Host

Mouse

Applications

WB, IHC, ELISA

Recommended dilution

WB 1:500-1:2000; IHC 1:200-1:1000; ELISA 1:10000

Clonality

Monoclonal

Conjugation

Unconjugated

Isotype

IgG1

Formulation

MTHFR Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.

Concentration

1 mg/ml

Purification

MTHFR Antibody was purified using affinity purification.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Methylenetetrahydrofolate reductase antibody,

Database links

Human UniProt/Swiss-Prot:P42898;Mouse UniPort/Swiss-Prot: Q9WU20;Rat UniProt/Swiss-Port: D4A7E8;Human Entrez Gene: 4524;Mouse Entrez Gene: 17769;Rat Entrez Gene: Rn.10494

Protein names

Methylenetetrahydrofolate reductase ,

Protein function

Catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. / 5-methyltetrahydrofolate + NAD(P)+ = 5,10-methylenetetrahydrofolate + NAD(P)H. / FAD / Allosterically regulated by S-adenosylmethionine. /

Involvement in disease

Methylenetetrahydrofolate reductase deficiency (MTHFRD) [MIM:236250]: Autosomal recessive disorder with a wide range of features including homocysteinuria, homocysteinemia [MIM:603174], developmental delay, severe mental retardation, perinatal death, psychiatric disturbances, and later-onset neurodegenerative disorders. . Note: The disease is caused by mutations affecting the gene represented in this entry.; Ischemic stroke (ISCHSTR) [MIM:601367]: A stroke is an acute neurologic event leading to death of neural tissue of the brain and resulting in loss of motor, sensory and/or cognitive function. Ischemic strokes, resulting from vascular occlusion, is considered to be a highly complex disease consisting of a group of heterogeneous disorders with multiple genetic and environmental risk factors. . Note: Disease susceptibility is associated with variations affecting the gene represented in this entry.; Neural tube defects, folate-sensitive (NTDFS) [MIM:601634]: The most common NTDs are open spina bifida (myelomeningocele) and anencephaly. . Note: Disease susceptibility is associated with variations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the methylenetetrahydrofolate reductase family.

Research area

All research areas>Signaling Intermediates>MTHFR
(View all antibody categories related to Signaling Intermediates)

Note

AntibodyPlus can customize MTHFR Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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