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Mouse Monoclonal MTHFR antibody [5D3] (STJ98257)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, IHC, ELISA
Recommended dilution: WB 1:500-1:2000; IHC 1:200-1:1000; ELISA 1:10000
Recommended protocols: check protocols
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Check alternative names for the antibodyExpand
MTHFR antibody,|5 10 methylenetetrahydrofolate reductase (NADPH) antibody|5 10 methylenetetrahydrofolate reductase antibody|Methylenetetrahydrofolate reductase (NAD(P)H) antibody|Methylenetetrahydrofolate reductase antibody|Methylenetetrahydrofolate reductase intermediate form antibody|MTHFR antibody|MTHR_HUMAN antibody|Anti-MTHFR antibody (ab55530)
SCBT cat No: sc-517229|sc-368720|sc-17079|
MTHFR Monoclonal Antibody
|Catalogue No.|| |
MTHFR Monoclonal Antibody detects endogenous levels of MTHFR protein.
Purified recombinant fragment of human MTHFR expressed in E Coli
WB, IHC, ELISA
|Recommended dilution|| |
WB 1:500-1:2000; IHC 1:200-1:1000; ELISA 1:10000
MTHFR Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.
MTHFR Antibody was purified using affinity purification.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Methylenetetrahydrofolate reductase antibody,
|Protein names|| |
Methylenetetrahydrofolate reductase ,
|Protein function|| |
Catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. / 5-methyltetrahydrofolate + NAD(P)+ = 5,10-methylenetetrahydrofolate + NAD(P)H. / FAD / Allosterically regulated by S-adenosylmethionine. /
|Involvement in disease|| |
Methylenetetrahydrofolate reductase deficiency (MTHFRD) [MIM:236250]: Autosomal recessive disorder with a wide range of features including homocysteinuria, homocysteinemia [MIM:603174], developmental delay, severe mental retardation, perinatal death, psychiatric disturbances, and later-onset neurodegenerative disorders. . Note: The disease is caused by mutations affecting the gene represented in this entry.; Ischemic stroke (ISCHSTR) [MIM:601367]: A stroke is an acute neurologic event leading to death of neural tissue of the brain and resulting in loss of motor, sensory and/or cognitive function. Ischemic strokes, resulting from vascular occlusion, is considered to be a highly complex disease consisting of a group of heterogeneous disorders with multiple genetic and environmental risk factors. . Note: Disease susceptibility is associated with variations affecting the gene represented in this entry.; Neural tube defects, folate-sensitive (NTDFS) [MIM:601634]: The most common NTDs are open spina bifida (myelomeningocele) and anencephaly. . Note: Disease susceptibility is associated with variations affecting the gene represented in this entry.
|Protein sequence and domain|| |
Belongs to the methylenetetrahydrofolate reductase family.
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St John’s Laboratory Ltd.
|Product type|| |
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