Mouse Monoclonal MyoD antibody [1C8] (STJ98263)

$379.00

Reactivity: Human
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Mouse Monoclonal MyoD antibody [1C8] (STJ98263)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-1:2000; ELISA 1:10000

Recommended protocols: check protocols

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Alternative names:

Check alternative names for the antibody

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MYOD1 antibody, BHLHC1 antibody, MYF3 antibody, MYOD antibody,|bHLHc1 antibody|Class C basic helix-loop-helix protein 1 antibody|MYF 3 antibody|Myf-3 antibody|MYF3 antibody|Myoblast determination protein 1 antibody|Myod 1 antibody|MYOD antibody|MYOD1 antibody|MYOD1_HUMAN antibody|Myogenic differentiation 1 antibody|Myogenic factor 3 antibody|Myogenic factor MYF 3 antibody|Myogenin D1 antibody|PUM antibody|Anti-MyoD1 antibody [5.2F] (ab16148)
SCBT cat No: sc-377186|

 

Name

MyoD Monoclonal Antibody

Catalogue No.

STJ98263

Reactivity

Human

Specificity

MyoD Monoclonal Antibody detects endogenous levels of MyoD protein.

Immunogen

Purified recombinant fragment of human MyoD expressed in E Coli

Host

Mouse

Applications

WB, ELISA

Recommended dilution

WB 1:500-1:2000; ELISA 1:10000

Clonality

Monoclonal

Conjugation

Unconjugated

Isotype

IgG1

Formulation

MyoD Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.

Concentration

1 mg/ml

Purification

MyoD Antibody was purified using affinity purification.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Myoblast determination protein 1 antibody, Class C basic helix-loop-helix protein 1 antibody, bHLHc1 antibody, Myogenic factor 3 antibody, Myf-3 antibody

Database links

Human UniProt/Swiss-Prot:P15172;Mouse UniPort/Swiss-Prot: P10085;Rat UniProt/Swiss-Port: Q02346;Human Entrez Gene: 4654;Mouse Entrez Gene: 17927;Rat Entrez Gene: Rn.9493

Protein names

Myoblast determination protein 1 , Class C basic helix-loop-helix protein 1 , bHLHc1 , Myogenic factor 3 , Myf-3

Protein function

Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. Together with MYF5 and MYOG, co-occupies muscle-specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into myoblasts. Interacts with and is inhibited by the twist protein. This interaction probably involves the basic domains of both proteins (By similarity).

Protein sequence and domain

Contains 1 bHLH (basic helix-loop-helix) domain.

Protein post-translational modifications

Phosphorylated by CDK9. This phosphorylation promotes its function in muscle differentiation. / Acetylated by a complex containing EP300 and PCAF. The acetylation is essential to activate target genes. Conversely, its deacetylation by SIRT1 inhibits its function (By similarity). / Ubiquitinated on the N-terminus; which is required for proteasomal degradation. / Methylation at Lys-104 by EHMT2/G9a inhibits myogenic activity.

Protein cellular localization

Nucleus

Research area

All research areas>Transcription Regulators>MyoD
(View all antibody categories related to Transcription Regulators)

Note

AntibodyPlus can customize MyoD Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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