Mouse Monoclonal N-CoR antibody [7A7A9] (STJ98269)

$379.00

Reactivity: Human
Applications: WB, IHC, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Mouse Monoclonal N-CoR antibody [7A7A9] (STJ98269)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IHC, ELISA

Recommended dilution: WB 1:500-1:2000; IHC 1:200-1:1000; ELISA 1:10000

Recommended protocols: check protocols

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Alternative names:

Check alternative names for the antibody

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NCOR1 antibody, KIAA1047 antibody,|hN CoR antibody|hNCoR antibody|KIAA1047 antibody|N CoR antibody|N Cor/SMRT corepressor Rip13 antibody|N CoR1 antibody|N-CoR antibody|N-CoR1 antibody|NCOR 1 antibody|NCoR antibody|Ncor1 antibody|NCOR1_HUMAN antibody|Nuclear receptor co repressor 1 antibody|Nuclear receptor corepressor 1 antibody|Retinoid X receptor interacting protein 13 antibody|RIP13 antibody|Rxrip13 antibody|thyroid hormone and retinoic acid receptor associated corepressor 1 antibody|TRAC 1 antibody|TRAC1 antibody|Anti-Nuclear Receptor Corepressor NCoR antibody – ChIP Grade (ab24552)
SCBT cat No: sc-293154|sc-1609|sc-8994|sc-1611|

 

Name

N-CoR Monoclonal Antibody

Catalogue No.

STJ98269

Reactivity

Human

Specificity

N-CoR Monoclonal Antibody detects endogenous levels of N-CoR protein.

Immunogen

Purified recombinant fragment of N-CoR (aa1-192) expressed in E Coli

Host

Mouse

Applications

WB, IHC, ELISA

Recommended dilution

WB 1:500-1:2000; IHC 1:200-1:1000; ELISA 1:10000

Clonality

Monoclonal

Conjugation

Unconjugated

Isotype

IgG1

Formulation

N-CoR Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.

Concentration

1 mg/ml

Purification

N-CoR Antibody was purified using affinity purification.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Nuclear receptor corepressor 1 antibody, N-CoR antibody, N-CoR1 antibody

Database links

Human UniProt/Swiss-Prot:O75376;Rat UniProt/Swiss-Port: A0A0G2K2B4;Human Entrez Gene: 9611;Mouse Entrez Gene: 20185;Rat Entrez Gene: Rn.24948

Protein names

Nuclear receptor corepressor 1 , N-CoR , N-CoR1

Protein function

Mediates transcriptional repression by certain nuclear receptors. Part of a complex which promotes histone deacetylation and the formation of repressive chromatin structures which may impede the access of basal transcription factors. Participates in the transcriptional repressor activity produced by BCL6.

Protein sequence and domain

The N-terminal region contains three independent domains that are capable of mediating transcriptional repression (RD1, RD2 and RD3). / The C-terminal region contains two separate nuclear receptor-interacting domains (ID1 and ID2), each of which contains a conserved sequence referred to as the CORNR box. This motif is necessary and sufficient for binding to unligated nuclear hormone receptors, while sequences flanking the CORNR box determine the precise nuclear hormone receptor specificity (By similarity). / Belongs to the N-CoR nuclear receptor corepressors family. / Contains 2 SANT domains.

Protein post-translational modifications

Ubiquitinated; mediated by SIAH2 and leading to its subsequent proteasomal degradation.

Protein cellular localization

Nucleus

Research area

All research areas>Steroid Receptors>N-CoR
(View all antibody categories related to Steroid Receptors)

Note

AntibodyPlus can customize N-CoR Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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