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Mouse Monoclonal NAC-1 antibody [6H2] (STJ98265)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, IHC, ELISA
Recommended dilution: WB 1:500-1:2000; IHC 1:200-1:1000; ELISA 1:10000
Recommended protocols: check protocols
Click or hover above images to see image description for NAC-1 Monoclonal Antibody.
Check alternative names for the antibodyExpand
NACC1 antibody, BTBD14B antibody, NAC1 antibody,|BEND8 antibody|BTB Domain Containing 14B antibody|BTB/POZ domain-containing protein 14B antibody|btbd14b antibody|FLJ37383 antibody|NAC-1 antibody|NAC1 antibody|Nacc1 antibody|NACC1_HUMAN antibody|Nucleus accumbens-associated protein 1 antibody|Anti-Nac1 antibody (ab29047)
SCBT cat No: sc-376216|sc-98638|
NAC-1 Monoclonal Antibody
|Catalogue No.|| |
NAC-1 Monoclonal Antibody detects endogenous levels of NAC-1 protein.
Purified recombinant fragment of human NAC-1 expressed in E Coli
WB, IHC, ELISA
|Recommended dilution|| |
WB 1:500-1:2000; IHC 1:200-1:1000; ELISA 1:10000
NAC-1 Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.
NAC-1 Antibody was purified using affinity purification.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Nucleus accumbens-associated protein 1 antibody, NAC-1 antibody, BTB/POZ domain-containing protein 14B antibody
|Protein names|| |
Nucleus accumbens-associated protein 1 , NAC-1 , BTB/POZ domain-containing protein 14B
|Protein function|| |
Functions as a transcriptional repressor. Seems to function as a transcriptional corepressor in neuronal cells through recruitment of HDAC3 and HDAC4. Contributes to tumor progression, and tumor cell proliferation and survival. This may be mediated at least in part through repressing transcriptional activity of GADD45GIP1. Required for recruiting the proteasome from the nucleus to the cytoplasm and dendritic spines.
|Protein tissue specificity|| |
Overexpressed in several types of carcinomas including ovarian serous carcinomas. Expression levels positively correlate with tumor recurrence in ovarian serous carcinomas, and intense immunoreactivity in primary ovarian tumors predicts early recurrence. Up-regulated in ovarian carcinomas after chemotherapy, suggesting a role in development of chemotherapy resistance in ovarian cancer.
|Protein sequence and domain|| |
Contains 1 BEN domain. / Contains 1 BTB (POZ) domain.
|Protein cellular localization|| |
Nucleus / Cytoplasm
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St John’s Laboratory Ltd.
|Product type|| |
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