Mouse Monoclonal NAC-1 antibody [6H2] (STJ98265)

$379.00

Reactivity: Human
Applications: WB, IHC, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Mouse Monoclonal NAC-1 antibody [6H2] (STJ98265)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IHC, ELISA

Recommended dilution: WB 1:500-1:2000; IHC 1:200-1:1000; ELISA 1:10000

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for NAC-1 Monoclonal Antibody.

Alternative names:

Check alternative names for the antibody

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NACC1 antibody, BTBD14B antibody, NAC1 antibody,|BEND8 antibody|BTB Domain Containing 14B antibody|BTB/POZ domain-containing protein 14B antibody|btbd14b antibody|FLJ37383 antibody|NAC-1 antibody|NAC1 antibody|Nacc1 antibody|NACC1_HUMAN antibody|Nucleus accumbens-associated protein 1 antibody|Anti-Nac1 antibody (ab29047)
SCBT cat No: sc-376216|sc-98638|

 

Name

NAC-1 Monoclonal Antibody

Catalogue No.

STJ98265

Reactivity

Human

Specificity

NAC-1 Monoclonal Antibody detects endogenous levels of NAC-1 protein.

Immunogen

Purified recombinant fragment of human NAC-1 expressed in E Coli

Host

Mouse

Applications

WB, IHC, ELISA

Recommended dilution

WB 1:500-1:2000; IHC 1:200-1:1000; ELISA 1:10000

Clonality

Monoclonal

Conjugation

Unconjugated

Isotype

IgG1

Formulation

NAC-1 Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.

Concentration

1 mg/ml

Purification

NAC-1 Antibody was purified using affinity purification.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Nucleus accumbens-associated protein 1 antibody, NAC-1 antibody, BTB/POZ domain-containing protein 14B antibody

Database links

Human UniProt/Swiss-Prot:Q96RE7;Mouse UniPort/Swiss-Prot: Q7TSZ8;Rat UniProt/Swiss-Port: O35260;Human Entrez Gene: 112939;Mouse Entrez Gene: 66830;Rat Entrez Gene: Rn.108186

Protein names

Nucleus accumbens-associated protein 1 , NAC-1 , BTB/POZ domain-containing protein 14B

Protein function

Functions as a transcriptional repressor. Seems to function as a transcriptional corepressor in neuronal cells through recruitment of HDAC3 and HDAC4. Contributes to tumor progression, and tumor cell proliferation and survival. This may be mediated at least in part through repressing transcriptional activity of GADD45GIP1. Required for recruiting the proteasome from the nucleus to the cytoplasm and dendritic spines.

Protein tissue specificity

Overexpressed in several types of carcinomas including ovarian serous carcinomas. Expression levels positively correlate with tumor recurrence in ovarian serous carcinomas, and intense immunoreactivity in primary ovarian tumors predicts early recurrence. Up-regulated in ovarian carcinomas after chemotherapy, suggesting a role in development of chemotherapy resistance in ovarian cancer.

Protein sequence and domain

Contains 1 BEN domain. / Contains 1 BTB (POZ) domain.

Protein cellular localization

Nucleus / Cytoplasm

Research area

All research areas>Transcription Regulators>BTBD14B
(View all antibody categories related to Transcription Regulators)

Note

AntibodyPlus can customize NAC-1 Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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