Mouse Monoclonal NM23-H1 antibody [4B2] (STJ98280)

$379.00

Reactivity: Human
Applications: WB, IHC, IF, FC, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Mouse Monoclonal NM23-H1 antibody [4B2] (STJ98280)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IHC, IF, FC, ELISA

Recommended dilution: WB 1:500-1:2000; IHC 1:200-1:1000; IF 1:200-1:1000; FC 1:200-1:400; ELISA 1:10000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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NME1 antibody, NDPKA antibody, NM23 antibody,|AWD antibody|AWD, drosophila, homolog of antibody|GAAD antibody|Granzyme A activated DNase antibody|Granzyme A-activated DNase antibody|GZMA activated DNase antibody|Metastasis inhibition factor NM23 antibody|NB antibody|NBS antibody|NDK A antibody|NDKA antibody|NDKA_HUMAN antibody|NDP kinase A antibody|NDPK-A antibody|NDPKA antibody|NM23 antibody|NM23 long variant, included antibody|nm23-H1 antibody|NM23-M1 antibody|NM23H1B, included antibody|NME/NM23 nucleoside diphosphate kinase 1 antibody|Nme1 antibody|NME1-NME2 spliced read-through transcript, included antibody|Non-metastatic cells 1, protein (NM23A) expressed in antibody|Nonmetastatic cells 1, protein expressed in antibody|Nonmetastatic protein 23 antibody|Nonmetastatic protein 23, homolog 1 antibody|Nucleoside diphosphate kinase A antibody|Tumor metastatic process-associated protein antibody|Anti-NM23A antibody (ab154547)
SCBT cat No: sc-343|sc-514515|sc-14787|sc-17586|sc-465|

 

Name

NM23-H1 Monoclonal Antibody

Catalogue No.

STJ98280

Reactivity

Human

Specificity

NM23-H1 Monoclonal Antibody detects endogenous levels of NM23-H1 protein.

Immunogen

Purified recombinant fragment of human NM23-H1 expressed in E Coli

Host

Mouse

Applications

WB, IHC, IF, FC, ELISA

Recommended dilution

WB 1:500-1:2000; IHC 1:200-1:1000; IF 1:200-1:1000; FC 1:200-1:400; ELISA 1:10000

Clonality

Monoclonal

Conjugation

Unconjugated

Isotype

IgG1

Formulation

NM23-H1 Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.

Concentration

1 mg/ml

Purification

NM23-H1 Antibody was purified using affinity purification.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Nucleoside diphosphate kinase A antibody, NDK A antibody, NDP kinase A antibody, Granzyme A-activated DNase antibody, GAAD antibody, Metastasis inhibition factor nm23 antibody, NM23-H1 antibody, Tumor metastatic process-associated protein antibody

Database links

Human UniProt/Swiss-Prot:P15531;Mouse UniPort/Swiss-Prot: P15532;Rat UniProt/Swiss-Port: Q05982;Human Entrez Gene: 4830;Mouse Entrez Gene: 18102;Rat Entrez Gene: Rn.6236

Protein names

Nucleoside diphosphate kinase A , NDK A , NDP kinase A , Granzyme A-activated DNase , GAAD , Metastasis inhibition factor nm23 , NM23-H1 , Tumor metastatic process-associated protein

Protein function

Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Possesses nucleoside-diphosphate kinase, serine/threonine-specific protein kinase, geranyl and farnesyl pyrophosphate kinase, histidine protein kinase and 3′-5′ exonuclease activities. Involved in cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor endocytosis, and gene expression. Required for neural development including neural patterning and cell fate determination. During GZMA-mediated cell death, works in concert with TREX1. NME1 nicks one strand of DNA and TREX1 removes bases from the free 3′ end to enhance DNA damage and prevent DNA end reannealing and rapid repair. / ATP + nucleoside diphosphate = ADP + nucleoside triphosphate. / Mg2+ / Autophosphorylation at His-118 increases serine/threonine protein kinase activity of the enzyme. Interaction with the SET complex inhibits the endonuclease activity.

Protein tissue specificity

Isoform 1 is expressed in heart, brain, placenta, lung, liver, skeletal muscle, pancreas, spleen and thymus. Expressed in lung carcinoma cell lines but not in normal lung tissues. Isoform 2 is ubiquitously expressed and its expression is also related to tumor differentiation.

Protein sequence and domain

Belongs to the NDK family.

Protein cellular localization

Cytoplasm / Nucleus

Research area

All research areas>Kinases and Phosphatases>nm23-H
(View all antibody categories related to Kinases and Phosphatases)

Note

AntibodyPlus can customize NM23-H1 Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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