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Mouse Monoclonal OLIG2 antibody [1G11] (STJ98289)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, IHC, IF, ELISA
Recommended dilution: WB 1:500-1:2000; IHC 1:200-1:1000; IF 1:200-1:1000; ELISA 1:10000
Recommended protocols: check protocols
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Check alternative names for the antibodyExpand
OLIG2 antibody, BHLHB1 antibody, BHLHE19 antibody, PRKCBP2 antibody, RACK17 antibody,|Basic domain helix loop helix protein class B 1 antibody|Basic helix loop helix protein class B 1 antibody|BHLHB antibody|bHLHB1 antibody|bHLHe19 antibody|Class B basic helix loop helix protein 1 antibody|Class B basic helix-loop-helix protein 1 antibody|class E basic helix loop helix protein 19 antibody|Class E basic helix-loop-helix protein 19 antibody|Human protein kinase C binding protein RACK17 antibody|Olig2 antibody|OLIG2_HUMAN antibody|Oligo2 antibody|Oligodendrocyte lineage transcription factor 2 antibody|Oligodendrocyte specific bHLH transcription factor 2 antibody|Oligodendrocyte transcription factor 2 antibody|OTTHUMP00000067569 antibody|OTTHUMP00000067570 antibody|PRKCBP2 antibody|Protein kinase C binding protein 2 antibody|Protein kinase C binding protein RACK17 antibody|Protein kinase C-binding protein 2 antibody|Protein kinase C-binding protein RACK17 antibody|RACK17 antibody|Anti-Olig2 antibody [EPR2673] (ab109186)
SCBT cat No: sc-293163|sc-19969|sc-48817|sc-19967|sc-133869|
OLIG2 Monoclonal Antibody
|Catalogue No.|| |
OLIG2 Monoclonal Antibody detects endogenous levels of OLIG2 protein.
Purified recombinant fragment of human OLIG2 expressed in E Coli
WB, IHC, IF, ELISA
|Recommended dilution|| |
WB 1:500-1:2000; IHC 1:200-1:1000; IF 1:200-1:1000; ELISA 1:10000
OLIG2 Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.
OLIG2 Antibody was purified using affinity purification.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Oligodendrocyte transcription factor 2 antibody, Oligo2 antibody, Class B basic helix-loop-helix protein 1 antibody, bHLHb1 antibody, Class E basic helix-loop-helix protein 19 antibody, bHLHe19 antibody, Protein kinase C-binding protein 2 antibody, Protein kinase C-binding protein RACK17 antibody
|Protein names|| |
Oligodendrocyte transcription factor 2 , Oligo2 , Class B basic helix-loop-helix protein 1 , bHLHb1 , Class E basic helix-loop-helix protein 19 , bHLHe19 , Protein kinase C-binding protein 2 , Protein kinase C-binding protein RACK17
|Protein function|| |
Required for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic motor neurons in the hindbrain. Cooperates with OLIG1 to establish the pMN domain of the embryonic neural tube. Antagonist of V2 interneuron and of NKX2-2-induced V3 interneuron development (By similarity).
|Protein tissue specificity|| |
Expressed in the brain, in oligodendrocytes. Strongly expressed in oligodendrogliomas, while expression is weak to moderate in astrocytomas. Expression in glioblastomas highly variable.
|Involvement in disease|| |
Note: A chromosomal aberration involving OLIG2 may be a cause of a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(14;21)(q11.2;q22) with TCRA. .
|Protein sequence and domain|| |
The bHLH is essential for interaction with NKX2-2. / Contains 1 bHLH (basic helix-loop-helix) domain.
|Protein cellular localization|| |
Nucleus / Cytoplasm
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St John’s Laboratory Ltd.
|Product type|| |
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