Mouse Monoclonal OTX2 antibody [1H12C4B5] (STJ98292)

$379.00

Reactivity: Human
Applications: WB, IHC, IF, FC, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Mouse Monoclonal OTX2 antibody [1H12C4B5] (STJ98292)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IHC, IF, FC, ELISA

Recommended dilution: WB 1:500-1:2000; IHC 1:200-1:1000; IF 1:200-1:1000; FC 1:200-1:400; ELISA 1:10000

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for OTX2 Monoclonal Antibody.

Alternative names:

Check alternative names for the antibody

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OTX2 antibody,|FLJ38361 antibody|Homeobox protein OTX 1 antibody|Homeobox protein OTX1 antibody|Homeobox protein OTX2 antibody|MCOPS 5 antibody|MCOPS5 antibody|MGC15736 antibody|MGC45000 antibody|Orthodenticle 1 antibody|Orthodenticle 2 antibody|Orthodenticle homeobox 1 antibody|Orthodenticle homeobox 2 antibody|Orthodenticle homolog 1 antibody|Orthodenticle homolog 2 (Drosophila) antibody|Orthodenticle homolog 2 antibody|Orthodenticle1 antibody|Orthodenticle2 antibody|Otx 1 antibody|Otx 2 antibody|otx1 antibody|OTX1_HUMAN antibody|otx2 antibody|OTX2_HUMAN antibody|Anti-Otx1 + Otx2 antibody – ChIP Grade (ab21990)
SCBT cat No: sc-514195|sc-292478|sc-30659|sc-133873|

 

Name

OTX2 Monoclonal Antibody

Catalogue No.

STJ98292

Reactivity

Human

Specificity

OTX2 Monoclonal Antibody detects endogenous levels of OTX2 protein.

Immunogen

Purified recombinant fragment of human OTX2 expressed in E Coli

Host

Mouse

Applications

WB, IHC, IF, FC, ELISA

Recommended dilution

WB 1:500-1:2000; IHC 1:200-1:1000; IF 1:200-1:1000; FC 1:200-1:400; ELISA 1:10000

Clonality

Monoclonal

Conjugation

Unconjugated

Isotype

IgG1

Formulation

OTX2 Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.

Concentration

1 mg/ml

Purification

OTX2 Antibody was purified using affinity purification.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Homeobox protein OTX2 antibody, Orthodenticle homolog 2 antibody

Database links

Human UniProt/Swiss-Prot:P32243;Rat UniProt/Swiss-Port: F2Z3S7;Human Entrez Gene: 5015;Mouse Entrez Gene: 18424;Rat Entrez Gene: Rn.35222

Protein names

Homeobox protein OTX2 , Orthodenticle homolog 2

Protein function

Probably plays a role in the development of the brain and the sense organs. Can bind to the BCD target sequence (BTS): 5′-TCTAATCCC-3′.

Protein tissue specificity

Expressed in brain.

Involvement in disease

Microphthalmia, syndromic, 5 (MCOPS5) [MIM:610125]: Patients manifest unilateral or bilateral microphthalmia/clinical anophthalmia and variable additional features including pituitary dysfunction, coloboma, microcornea, cataract, retinal dystrophy, hypoplasia or agenesis of the optic nerve, agenesis of the corpus callosum, developmental delay, joint laxity, hypotonia, and seizures. Microphthalmia is a disorder of eye formation, ranging from small size of a single eye to complete bilateral absence of ocular tissues (anophthalmia). In many cases, microphthalmia/anophthalmia occurs in association with syndromes that include non-ocular abnormalities. . Note: The disease is caused by mutations affecting the gene represented in this entry.; Pituitary hormone deficiency, combined, 6 (CPHD6) [MIM:613986]: Combined pituitary hormone deficiency is defined as the impaired production of growth hormone and one or more of the other five anterior pituitary hormones. CPHD6 patients manifest neonatal hypoglycemia, and deficiencies of growth hormone, thyroid-stimulating hormone, luteinizing hormone, follicle stimulating hormone and adrenocorticotropic hormone. . Note: The disease is caused by mutations affecting the gene represented in this entry.; Retinal dystrophy, early-onset, with or without pituitary dysfunction (RDEOP) [MIM:610125]: An autosomal dominant ocular disease characterized by pattern dystrophy of the retinal pigment epithelium, and photoreceptor degeneration. Mild developmental anomalies include optic nerve head dysplasia, microcornea, and Rathke’s cleft cyst. Some patients manifest pituary dysfunction. . Note: The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the paired homeobox family. Bicoid subfamily. / Contains 1 homeobox DNA-binding domain.

Protein cellular localization

Nucleus

Research area

All research areas>Homeodomain Proteins>OTX2
(View all antibody categories related to Homeodomain Proteins)

Note

AntibodyPlus can customize OTX2 Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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