Mouse Monoclonal PARL antibody [8C4B2; 1H12E10] (STJ98307)

$379.00

Reactivity: Human
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

Clear
-$50 as credit for submitting review for primary antibody
Shipping notice:
Product will be delivered in 6 to 8 Business Days

Mouse Monoclonal PARL antibody [8C4B2; 1H12E10] (STJ98307)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-1:2000; ELISA 1:10000

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for PARL Monoclonal Antibody.

Alternative names:

Check alternative names for the antibody

Expand

PARL antibody, PSARL antibody, PRO2207 antibody,|Mitochondrial intramembrane cleaving protease PARL antibody|Mitochondrial intramembrane-cleaving protease PARL antibody|P-beta antibody|parl antibody|PARL_HUMAN antibody|Pbeta antibody|presenilin associated rhomboid-like antibody|Presenilins associated rhomboid-like protein antibody|PRO2207 antibody|PSARL antibody|PSARL1 antibody|PSENIP2 antibody|RHBDS1 antibody|Rhomboid 7 homolog 1 antibody|Anti-PARL antibody (ab45231)
SCBT cat No: sc-133884|sc-514836|

 

Name

PARL Monoclonal Antibody

Catalogue No.

STJ98307

Reactivity

Human

Specificity

PARL Monoclonal Antibody detects endogenous levels of PARL protein.

Immunogen

Purified recombinant fragment of PARL (aa112-167) expressed in E Coli

Host

Mouse

Applications

WB, ELISA

Recommended dilution

WB 1:500-1:2000; ELISA 1:10000

Clonality

Monoclonal

Conjugation

Unconjugated

Isotype

IgG2b

Formulation

PARL Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.

Concentration

1 mg/ml

Purification

PARL Antibody was purified using affinity purification.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Presenilins-associated rhomboid-like protein, mitochondrial antibody, Mitochondrial intramembrane cleaving protease PARL antibody

Database links

Human UniProt/Swiss-Prot:Q9H300;Mouse UniPort/Swiss-Prot: Q5XJY4;Rat UniProt/Swiss-Port: Q3B8P0;Human Entrez Gene: 55486;Mouse Entrez Gene: 381038;Rat Entrez Gene: Rn.7053

Protein names

Presenilins-associated rhomboid-like protein, mitochondrial , Mitochondrial intramembrane cleaving protease PARL

Protein function

Required for the control of apoptosis during postnatal growth. Essential for proteolytic processing of an antiapoptotic form of OPA1 which prevents the release of mitochondrial cytochrome c in response to intrinsic apoptoptic signals (By similarity). Promotes changes in mitochondria morphology regulated by phosphorylation of P-beta domain. / Cleaves type-1 transmembrane domains using a catalytic dyad composed of serine and histidine that are contributed by different transmembrane domains.

Protein sequence and domain

Belongs to the peptidase S54 family.

Protein post-translational modifications

P-beta is proteolytically processed (beta-cleavage) in a PARL-dependent manner. The cleavage is inhibited when residues Ser-65, Thr-69 and Ser-70 are all phosphorylated.

Protein cellular localization

Mitochondrion inner membrane / Multi-pass membrane protein / Nucleus

Research area

All research areas>Synthesis and Degradation>PARL
(View all antibody categories related to Synthesis and Degradation)

Note

AntibodyPlus can customize PARL Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

Reviews


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review

There are no reviews for this product yet.
By submitting a review, get following benefits:

1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!

view database submit reviews

There is no extra validation for this product yet.
Check other extra validated antibodies below:



Welcome to AntibodyPlus!