No products in the cart.
Mouse Monoclonal PARL antibody [8C4B2; 1H12E10] (STJ98307)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, ELISA
Recommended dilution: WB 1:500-1:2000; ELISA 1:10000
Recommended protocols: check protocols
Click or hover above images to see image description for PARL Monoclonal Antibody.
Check alternative names for the antibodyExpand
PARL antibody, PSARL antibody, PRO2207 antibody,|Mitochondrial intramembrane cleaving protease PARL antibody|Mitochondrial intramembrane-cleaving protease PARL antibody|P-beta antibody|parl antibody|PARL_HUMAN antibody|Pbeta antibody|presenilin associated rhomboid-like antibody|Presenilins associated rhomboid-like protein antibody|PRO2207 antibody|PSARL antibody|PSARL1 antibody|PSENIP2 antibody|RHBDS1 antibody|Rhomboid 7 homolog 1 antibody|Anti-PARL antibody (ab45231)
SCBT cat No: sc-133884|sc-514836|
PARL Monoclonal Antibody
|Catalogue No.|| |
PARL Monoclonal Antibody detects endogenous levels of PARL protein.
Purified recombinant fragment of PARL (aa112-167) expressed in E Coli
|Recommended dilution|| |
WB 1:500-1:2000; ELISA 1:10000
PARL Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.
PARL Antibody was purified using affinity purification.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Presenilins-associated rhomboid-like protein, mitochondrial antibody, Mitochondrial intramembrane cleaving protease PARL antibody
|Protein names|| |
Presenilins-associated rhomboid-like protein, mitochondrial , Mitochondrial intramembrane cleaving protease PARL
|Protein function|| |
Required for the control of apoptosis during postnatal growth. Essential for proteolytic processing of an antiapoptotic form of OPA1 which prevents the release of mitochondrial cytochrome c in response to intrinsic apoptoptic signals (By similarity). Promotes changes in mitochondria morphology regulated by phosphorylation of P-beta domain. / Cleaves type-1 transmembrane domains using a catalytic dyad composed of serine and histidine that are contributed by different transmembrane domains.
|Protein sequence and domain|| |
Belongs to the peptidase S54 family.
|Protein post-translational modifications|| |
P-beta is proteolytically processed (beta-cleavage) in a PARL-dependent manner. The cleavage is inhibited when residues Ser-65, Thr-69 and Ser-70 are all phosphorylated.
|Protein cellular localization|| |
Mitochondrion inner membrane / Multi-pass membrane protein / Nucleus
AntibodyPlus can customize PARL Antibody according to your requirement, including bulk product size,etc. Please contact email@example.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.
St John’s Laboratory Ltd.
|Product type|| |
There are no reviews for this product yet.
By submitting a review, get following benefits:
1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!
There is no extra validation for this product yet.
Check other extra validated antibodies below: