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Mouse Monoclonal PBEF antibody [4E11C9] (STJ98312)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, ELISA
Recommended dilution: WB 1:500-1:2000; ELISA 1:10000
Recommended protocols: check protocols
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Check alternative names for the antibodyExpand
NAMPT antibody, PBEF antibody, PBEF1 antibody,|1110035O14Rik antibody|AI314458 antibody|AI480535 antibody|DKFZP666B131 antibody|EC 22.214.171.124 antibody|MGC117256 antibody|NAmPRTase antibody|Nampt antibody|NAMPT_HUMAN antibody|Nicotinamide phosphoribosyltransferase antibody|PBEF 1 antibody|PBEF antibody|PBEF1 antibody|Pre B cell colony enhancing factor 1 antibody|Pre B cell colony enhancing factor antibody|Pre B cell enhancing factor antibody|Pre-B cell-enhancing factor antibody|Pre-B-cell colony-enhancing factor 1 antibody|VF antibody|Visfatin antibody|Anti-Visfatin antibody (ab45890)
SCBT cat No: sc-130058|sc-46440|sc-166866|sc-393444|sc-393443|sc-393510|sc-166946|sc-67020|
PBEF Monoclonal Antibody
|Catalogue No.|| |
PBEF Monoclonal Antibody detects endogenous levels of PBEF protein.
Purified recombinant fragment of PBEF expressed in E Coli
|Recommended dilution|| |
WB 1:500-1:2000; ELISA 1:10000
PBEF Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.
PBEF Antibody was purified using affinity purification.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Nicotinamide phosphoribosyltransferase antibody, NAmPRTase antibody, Nampt antibody, Pre-B-cell colony-enhancing factor 1 antibody, Pre-B cell-enhancing factor antibody, Visfatin antibody
|Protein names|| |
Nicotinamide phosphoribosyltransferase , NAmPRTase , Nampt , Pre-B-cell colony-enhancing factor 1 , Pre-B cell-enhancing factor , Visfatin
|Protein function|| |
Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway. The secreted form behaves both as a cytokine with immunomodulating properties and an adipokine with anti-diabetic properties, it has no enzymatic activity, partly because of lack of activation by ATP, which has a low level in extracellular space and plasma. Plays a role in the modulation of circadian clock function. NAMPT-dependent oscillatory production of NAD regulates oscillation of clock target gene expression by releasing the core clock component: CLOCK-ARNTL/BMAL1 heterodimer from NAD-dependent SIRT1-mediated suppression (By similarity). / Nicotinamide D-ribonucleotide + diphosphate = nicotinamide + 5-phospho-alpha-D-ribose 1-diphosphate. / Inhibited by FK866. FK866 competes for the same binding site as nicotinamide, but due to its very low dissociation rate, it is essentially an irreversible inhibitor. /
|Protein tissue specificity|| |
Expressed in large amounts in bone marrow, liver tissue, and muscle. Also present in heart, placenta, lung, and kidney tissues.
|Protein sequence and domain|| |
Belongs to the NAPRTase family.
|Protein cellular localization|| |
Nucleus / Cytoplasm / Secreted
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St John’s Laboratory Ltd.
|Product type|| |
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