Mouse Monoclonal PP1beta antibody (STJ98534)

$379.00

Reactivity: Human, Mouse, Rat, Chicken, Dog, Pig
Applications: WB
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Mouse Monoclonal PP1beta antibody (STJ98534)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB

Recommended dilution: WB 1:1000-1:2000

Recommended protocols: check protocols

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Alternative names:

Check alternative names for the antibody

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PPP1CB antibody,|MGC3672 antibody|PP 1B antibody|PP-1B antibody|PP1B antibody|PP1B_HUMAN antibody|PP1beta antibody|PPP1CB antibody|PPP1CD antibody|Protein phosphatase 1 beta antibody|Protein phosphatase 1 catalytic subunit beta isoform antibody|Protein phosphatase 1 delta antibody|Protein phosphatase 1, catalytic subunit, beta isozyme antibody|Protein phosphatase 1, catalytic subunit, delta isoform antibody|Serine threonine protein phosphatase PP1 beta catalytic subunit antibody|Serine/threonine-protein phosphatase PP1-beta catalytic subunit antibody|Anti-Protein Phosphatase 1 beta antibody [EP1804Y] (ab53315)
SCBT cat No: sc-517233|sc-365678|sc-6106|sc-373782|sc-377125|sc-373783|sc-6107|

 

Name

PP1beta Monoclonal Antibody

Catalogue No.

STJ98534

Reactivity

Human, Mouse, Rat, Chicken, Dog, Pig

Specificity

PP1beta Monoclonal Antibody detects endogenous levels of PP1beta protein.

Immunogen

Purified recombinant human PP1beta protein fragments expressed in Ecoli

Host

Mouse

Applications

WB

Recommended dilution

WB 1:1000-1:2000

Clonality

Monoclonal

Conjugation

Unconjugated

Formulation

PP1beta Antibody was tube-contained. Purified in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol.

Concentration

1 mg/ml

Purification

PP1beta Antibody was purified using affinity purification.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Serine/threonine-protein phosphatase PP1-beta catalytic subunit antibody, PP-1B antibody, PPP1CD antibody,

Database links

Human UniProt/Swiss-Prot:P62140;Mouse UniPort/Swiss-Prot: P62141;Rat UniProt/Swiss-Port: P62142;Human Entrez Gene: 5500;Mouse Entrez Gene: 19046;Rat Entrez Gene: Rn.128769

Protein names

Serine/threonine-protein phosphatase PP1-beta catalytic subunit , PP-1B , PPP1CD ,

Protein function

Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase (PP1) is essential for cell division, it participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. In balance with CSNK1D and CSNK1E, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation. May dephosphorylate CSNK1D and CSNK1E. Dephosphorylates the ‘Ser-418’ residue of FOXP3 in regulatory T-cells (Treg) from patients with rheumatoid arthritis, thereby inactivating FOXP3 and rendering Treg cells functionally defective . / [a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate. / [Myosin light-chain] phosphate + H2O = [myosin light-chain] + phosphate. / Mn2+ / Inhibited by the toxins okadaic acid, tautomycin and microcystin Leu-Arg (By similarity). The phosphatase activity of the PPP1R15A-PP1 complex toward EIF2S1 is specifically inhibited by Salubrinal, a drug that protects cells from endoplasmic reticulum stress.

Protein tissue specificity

Up-regulated in synovial fluid mononuclear cells and peripheral blood mononuclear cells from patients with rheumatoid arthritis.

Protein sequence and domain

Belongs to the PPP phosphatase family. PP-1 subfamily.

Protein cellular localization

Cytoplasm / Nucleus / Nucleus > nucleoplasm / Nucleus > nucleolus

Research area

All research areas>Kinases and Phosphatases>PP1 beta
(View all antibody categories related to Kinases and Phosphatases)

Note

AntibodyPlus can customize PP1beta Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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