Mouse Monoclonal Rab 10 antibody [4E2] (STJ98346)

$379.00

Reactivity: Human, Mouse
Applications: WB, IF, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

Clear
-$50 as credit for submitting review for primary antibody
Shipping notice:
Product will be delivered in 6 to 8 Business Days

Mouse Monoclonal Rab 10 antibody [4E2] (STJ98346)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IF, ELISA

Recommended dilution: WB 1:500-1:2000; IF 1:200-1:1000; ELISA 1:10000

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rab 10 Monoclonal Antibody.

Alternative names:

Check alternative names for the antibody

Expand

RAB10 antibody,|GTP binding protein RAB10 antibody||Anti-RAB10 antibody [4E2] (ab104859)
SCBT cat No: sc-101429|sc-6564|

 

Name

Rab 10 Monoclonal Antibody

Catalogue No.

STJ98346

Reactivity

Human, Mouse

Specificity

Rab 10 Monoclonal Antibody detects endogenous levels of Rab 10 protein.

Immunogen

Purified recombinant fragment of human Rab 10 expressed in E Coli

Host

Mouse

Applications

WB, IF, ELISA

Recommended dilution

WB 1:500-1:2000; IF 1:200-1:1000; ELISA 1:10000

Clonality

Monoclonal

Conjugation

Unconjugated

Isotype

IgG1

Formulation

Rab 10 Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.

Concentration

1 mg/ml

Purification

Rab 10 Antibody was purified using affinity purification.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Ras-related protein Rab-10 antibody

Database links

Human UniProt/Swiss-Prot:P61026;Mouse UniPort/Swiss-Prot: P61027;Rat UniProt/Swiss-Port: Q5RKJ9;Human Entrez Gene: 10890;Mouse Entrez Gene: 19325;Rat Entrez Gene: Rn.65864

Protein names

Ras-related protein Rab-10

Protein function

The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (By similarity). That Rab is mainly involved in the biosynthetic transport of proteins from the Golgi to the plasma membrane. Regulates, for instance, SLC2A4/GLUT4 glucose transporter-enriched vesicles delivery to the plasma membrane. In parallel, it regulates the transport of TLR4, a toll-like receptor to the plasma membrane and therefore may be important for innate immune response. Plays also a specific role in asymmetric protein transport to the plasma membrane within the polarized neuron and epithelial cells. In neurons, it is involved in axonogenesis through regulation of vesicular membrane trafficking toward the axonal plasma membrane while in epithelial cells, it regulates transport from the Golgi to the basolateral membrane. Moreover, may play a role in the basolateral recycling pathway and in phagosome maturation. According to PubMed:23263280, may play a role in endoplasmic reticulum dynamics and morphology controlling tubulation along microtubules and tubules fusion. / Rab activation is generally mediated by a guanine exchange factor (GEF), while inactivation through hydrolysis of bound GTP is catalyzed by a GTPase activating protein (GAP) (By similarity). That Rab is activated by the DENND4C guanine exchange factor (GEF).

Protein sequence and domain

Belongs to the small GTPase superfamily. Rab family.

Protein cellular localization

Cytoplasmic vesicle membrane / Golgi apparatus membrane / Golgi apparatus > trans-Golgi network membrane / Endosome membrane / Recycling endosome membrane / Cytoplasmic vesicle > phagosome membrane / Cell projection > cilium / Endoplasmic reticulum membrane

Research area

All research areas>GDP/GTP Binding Proteins>Rab
(View all antibody categories related to GDP/GTP Binding Proteins)

Note

AntibodyPlus can customize Rab 10 Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

Reviews


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review

There are no reviews for this product yet.
By submitting a review, get following benefits:

1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!

view database submit reviews

There is no extra validation for this product yet.
Check other extra validated antibodies below:



Welcome to AntibodyPlus!