Mouse Monoclonal Rictor antibody [4H5] (STJ98363)

$379.00

Reactivity: Human, Mouse, Monkey
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Mouse Monoclonal Rictor antibody [4H5] (STJ98363)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-1:2000; ELISA 1:10000

Recommended protocols: check protocols

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Alternative names:

Check alternative names for the antibody

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RICTOR antibody, KIAA1999 antibody,|AVO3 antibody|AVO3 homolog antibody|DKFZp686B11164 antibody|hAVO3 antibody|KIAA1999 antibody|Likely ortholog of mouse TORC2 specific protein AVO3 (S. cerevisiae) antibody|mAVO3 antibody|MGC39830 antibody|PIA antibody|Pianissimo antibody|Rapamycin insensitive companion of mTOR antibody|Rapamycin-insensitive companion of mTOR antibody|Rictor antibody|RICTR antibody|RICTR_HUMAN antibody|RPTOR independent companion of MTOR complex 2 antibody|TORC2 specific protein AVO3 antibody|Anti-RICTOR antibody (ab70374)
SCBT cat No: sc-81538|sc-271081|sc-99004|sc-50678|sc-130865|

 

Name

Rictor Monoclonal Antibody

Catalogue No.

STJ98363

Reactivity

Human, Mouse, Monkey

Specificity

Rictor Monoclonal Antibody detects endogenous levels of Rictor protein.

Immunogen

Purified recombinant fragment of human Rictor expressed in E Coli

Host

Mouse

Applications

WB, ELISA

Recommended dilution

WB 1:500-1:2000; ELISA 1:10000

Clonality

Monoclonal

Conjugation

Unconjugated

Isotype

IgG1

Formulation

Rictor Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.

Concentration

1 mg/ml

Purification

Rictor Antibody was purified using affinity purification.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Rapamycin-insensitive companion of mTOR antibody, AVO3 homolog antibody, hAVO3 antibody

Database links

Human UniProt/Swiss-Prot:Q6R327;Mouse UniPort/Swiss-Prot: Q6QI06;Rat UniProt/Swiss-Port: F1M4J0;Human Entrez Gene: 253260;Mouse Entrez Gene: 78757;

Protein names

Rapamycin-insensitive companion of mTOR , AVO3 homolog , hAVO3

Protein function

Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. mTORC2 plays a critical role in AKT1 ‘Ser-473’ phosphorylation, which may facilitate the phosphorylation of the activation loop of AKT1 on ‘Thr-308’ by PDK1 which is a prerequisite for full activation. mTORC2 regulates the phosphorylation of SGK1 at ‘Ser-422’. mTORC2 also modulates the phosphorylation of PRKCA on ‘Ser-657’. Plays an essential role in embryonic growth and development.

Protein sequence and domain

Belongs to the RICTOR family.

Protein post-translational modifications

Phosphorylated by MTOR; when part of mTORC2. Phosphorylated at Thr-1135 by RPS6KB1; phosphorylation of RICTOR inhibits mTORC2 and AKT1 signaling.

Research area

All research areas>Signaling Intermediates>Rictor
(View all antibody categories related to Signaling Intermediates)

Note

AntibodyPlus can customize Rictor Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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