Mouse Monoclonal Rtn-3 antibody [1E11] (STJ98370)

$379.00

Reactivity: Human
Applications: IF, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Mouse Monoclonal Rtn-3 antibody [1E11] (STJ98370)

Supplier: St John’s Laboratory Ltd.

Recommended applications: IF, ELISA

Recommended dilution: IF 1:200-1:1000; ELISA 1:10000

Recommended protocols: check protocols

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Alternative names:

Check alternative names for the antibody

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RTN3 antibody, ASYIP antibody, NSPL2 antibody,|ASYIP antibody|Neuroendocrine specific protein like 2 antibody|Neuroendocrine-specific protein-like 2 antibody|Neuroendocrine-specific protein-like II antibody|NSP like protein II antibody|NSP-like protein 2 antibody|NSP-like protein II antibody|NSPL2 antibody|NSPLII antibody|Reticulon 3 antibody|Reticulon-3 antibody|Reticulon3 antibody|Rtn3 antibody|RTN3_HUMAN antibody|Anti-RTN3 antibody – C-terminal (ab187764)
SCBT cat No: sc-374599|sc-33599|

 

Name

Rtn-3 Monoclonal Antibody

Catalogue No.

STJ98370

Reactivity

Human

Specificity

Rtn-3 Monoclonal Antibody detects endogenous levels of Rtn-3 protein.

Immunogen

Purified recombinant fragment of Rtn-3 expressed in E Coli

Host

Mouse

Applications

IF, ELISA

Recommended dilution

IF 1:200-1:1000; ELISA 1:10000

Clonality

Monoclonal

Conjugation

Unconjugated

Isotype

IgG2a

Formulation

Rtn-3 Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.

Concentration

1 mg/ml

Purification

Rtn-3 Antibody was purified using affinity purification.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Reticulon-3 antibody, Homolog of ASY protein antibody, HAP antibody, Neuroendocrine-specific protein-like 2 antibody, NSP-like protein 2 antibody, Neuroendocrine-specific protein-like II antibody, NSP-like protein II antibody, NSPLII antibody

Database links

Human UniProt/Swiss-Prot:O95197;Mouse UniPort/Swiss-Prot: Q9ES97;Rat UniProt/Swiss-Port: Q6RJR6;Human Entrez Gene: 10313;Mouse Entrez Gene: 20168;Rat Entrez Gene: Rn.11652

Protein names

Reticulon-3 , Homolog of ASY protein , HAP , Neuroendocrine-specific protein-like 2 , NSP-like protein 2 , Neuroendocrine-specific protein-like II , NSP-like protein II , NSPLII

Protein function

May be involved in membrane trafficking in the early secretory pathway. Inhibits BACE1 activity and amyloid precursor protein processing. May induce caspase-8 cascade and apoptosis. May favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress. In case of enteroviruses infection, RTN3 may be involved in the viral replication or pathogenesis. Induces the formation of endoplasmic reticulum tubules .

Protein tissue specificity

Isoform 3 is widely expressed, with highest levels in brain, where it is enriched in neuronal cell bodies from gray matter (at protein level). Three times more abundant in macula than in peripheral retina. Isoform 1 is expressed at high levels in brain and at low levels in skeletal muscle. Isoform 2 is only found in melanoma.

Protein sequence and domain

Contains 1 reticulon domain.

Protein cellular localization

Endoplasmic reticulum membrane / Multi-pass membrane protein / Golgi apparatus membrane / Multi-pass membrane protein

Research area

All research areas>Neurobiology>Rtn-3
(View all antibody categories related to Neurobiology)

Note

AntibodyPlus can customize Rtn-3 Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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