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Mouse Monoclonal Rtn-3 antibody [1E11] (STJ98370)
Supplier: St John’s Laboratory Ltd.
Recommended applications: IF, ELISA
Recommended dilution: IF 1:200-1:1000; ELISA 1:10000
Recommended protocols: check protocols
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Check alternative names for the antibodyExpand
RTN3 antibody, ASYIP antibody, NSPL2 antibody,|ASYIP antibody|Neuroendocrine specific protein like 2 antibody|Neuroendocrine-specific protein-like 2 antibody|Neuroendocrine-specific protein-like II antibody|NSP like protein II antibody|NSP-like protein 2 antibody|NSP-like protein II antibody|NSPL2 antibody|NSPLII antibody|Reticulon 3 antibody|Reticulon-3 antibody|Reticulon3 antibody|Rtn3 antibody|RTN3_HUMAN antibody|Anti-RTN3 antibody – C-terminal (ab187764)
SCBT cat No: sc-374599|sc-33599|
Rtn-3 Monoclonal Antibody
|Catalogue No.|| |
Rtn-3 Monoclonal Antibody detects endogenous levels of Rtn-3 protein.
Purified recombinant fragment of Rtn-3 expressed in E Coli
|Recommended dilution|| |
IF 1:200-1:1000; ELISA 1:10000
Rtn-3 Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.
Rtn-3 Antibody was purified using affinity purification.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Reticulon-3 antibody, Homolog of ASY protein antibody, HAP antibody, Neuroendocrine-specific protein-like 2 antibody, NSP-like protein 2 antibody, Neuroendocrine-specific protein-like II antibody, NSP-like protein II antibody, NSPLII antibody
|Protein names|| |
Reticulon-3 , Homolog of ASY protein , HAP , Neuroendocrine-specific protein-like 2 , NSP-like protein 2 , Neuroendocrine-specific protein-like II , NSP-like protein II , NSPLII
|Protein function|| |
May be involved in membrane trafficking in the early secretory pathway. Inhibits BACE1 activity and amyloid precursor protein processing. May induce caspase-8 cascade and apoptosis. May favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress. In case of enteroviruses infection, RTN3 may be involved in the viral replication or pathogenesis. Induces the formation of endoplasmic reticulum tubules .
|Protein tissue specificity|| |
Isoform 3 is widely expressed, with highest levels in brain, where it is enriched in neuronal cell bodies from gray matter (at protein level). Three times more abundant in macula than in peripheral retina. Isoform 1 is expressed at high levels in brain and at low levels in skeletal muscle. Isoform 2 is only found in melanoma.
|Protein sequence and domain|| |
Contains 1 reticulon domain.
|Protein cellular localization|| |
Endoplasmic reticulum membrane / Multi-pass membrane protein / Golgi apparatus membrane / Multi-pass membrane protein
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St John’s Laboratory Ltd.
|Product type|| |
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