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Mouse Monoclonal SAF-B antibody (STJ98547)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB
Recommended dilution: WB 1:1000-1:2000
Recommended protocols: check protocols
Click or hover above images to see image description for SAF-B Monoclonal Antibody.
Check alternative names for the antibodyExpand
SAFB antibody, HAP antibody, HET antibody, SAFB1 antibody,|DKFZp779C1727 antibody|glutathione S transferase fusion protein antibody|HAP antibody|HET antibody|HSP27 ERE TATA binding protein antibody|HSP27 ERE-TATA-binding protein antibody|HSP27 estrogen response element-TATA box-binding protein antibody|SAF B antibody|SAF-B antibody|SAF-B1 antibody|SAFB 1 antibody|SAFB antibody|SAFB1 antibody|SAFB1_HUMAN antibody|Scaffold attachment factor B1 antibody|Anti-SAFB antibody [EPR13588] – C-terminal (ab187650)
SCBT cat No: sc-393455|sc-514963|sc-393689|
SAF-B Monoclonal Antibody
|Catalogue No.|| |
SAF-B Monoclonal Antibody detects endogenous levels of SAF-B protein.
Purified recombinant human SAF-B protein fragments expressed in Ecoli
|Recommended dilution|| |
SAF-B Antibody was tube-contained. Purified in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Scaffold attachment factor B1 antibody, SAF-B antibody, SAF-B1 antibody, HSP27 estrogen response element-TATA box-binding protein antibody, HSP27 ERE-TATA-binding protein antibody
|Protein names|| |
Scaffold attachment factor B1 , SAF-B , SAF-B1 , HSP27 estrogen response element-TATA box-binding protein , HSP27 ERE-TATA-binding protein
|Protein function|| |
Binds to scaffold/matrix attachment region (S/MAR) DNA and forms a molecular assembly point to allow the formation of a ‘transcriptosomal’ complex (consisting of SR proteins and RNA polymerase II) coupling transcription and RNA processing (By similarity). Can function as an estrogen receptor corepressor and can also bind to the HSP27 promoter and decrease its transcription. When associated with RBMX, binds to and stimulates transcription from the SREBF1 promoter (By similarity). Can inhibit cell proliferation.
|Protein tissue specificity|| |
Ubiquitous. Expressed at high levels in the CNS and at low levels in the liver. Expressed in a wide number of breast cancer cell lines.
|Protein sequence and domain|| |
Contains 1 RRM (RNA recognition motif) domain. / Contains 1 SAP domain.
|Protein post-translational modifications|| |
Sumoylated by PIAS1 with SUMO1 and SUMO2/3, desumoylated by SENP1. Sumoylation is required for transcriptional repressor activity.
|Protein cellular localization|| |
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St John’s Laboratory Ltd.
|Product type|| |
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