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Mouse Monoclonal SCP-3 antibody (STJ98548)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB
Recommended dilution: WB 1:1000-1:2000
Recommended protocols: check protocols
Click or hover above images to see image description for SCP-3 Monoclonal Antibody.
Check alternative names for the antibodyExpand
SYCP3 antibody, SCP3 antibody,|choline phosphotransferase 1 antibody|chpt1 antibody|COR 1 antibody|COR1 antibody|MGC71888 antibody|RNASCP3 antibody|SCP 3 antibody|SCP-3 antibody|SCP3 antibody|SPGF4 antibody|Sycp 3 antibody|Sycp3 antibody|SYCP3_HUMAN antibody|Synaptonemal complex protein 3 antibody|Anti-SCP3 antibody (ab15093)
SCBT cat No: To be updated
SCP-3 Monoclonal Antibody
|Catalogue No.|| |
SCP-3 Monoclonal Antibody detects endogenous levels of SCP-3 protein.
Purified recombinant human SCP-3 protein fragments expressed in Ecoli
|Recommended dilution|| |
SCP-3 Antibody was tube-contained. Purified in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Synaptonemal complex protein 3 antibody, SCP-3 antibody
|Protein names|| |
Synaptonemal complex protein 3 , SCP-3
|Protein function|| |
Component of the synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Required for centromere pairing during meiosis in male germ cells (By similarity). Required for normal meiosis during spermatogenesis and male fertility . Plays a lesser role in female fertility. Required for efficient phosphorylation of HORMAD1 and HORMAD2 (By similarity).
|Protein tissue specificity|| |
|Involvement in disease|| |
Spermatogenic failure 4 (SPGF4) [MIM:270960]: An infertility disorder characterized by azoospermia, a condition of having no sperm present in the ejaculate. Testicular histology shows arrest of spermatogenesis at the pachytene stage of primary spermatocytes. . Note: The disease is caused by mutations affecting the gene represented in this entry.; Pregnancy loss, recurrent, 4 (RPRGL4) [MIM:270960]: A common complication of pregnancy, resulting in spontaneous abortion before the fetus has reached viability. The term includes all miscarriages from the time of conception until 24 weeks of gestation. Recurrent pregnancy loss is defined as 3 or more consecutive spontaneous abortions. . Note: Disease susceptibility is associated with variations affecting the gene represented in this entry.
|Protein sequence and domain|| |
Composed of a long central coiled coil domain. The N-terminal and C-terminal regions interact with DNA. / Belongs to the XLR/SYCP3 family.
|Protein post-translational modifications|| |
|Protein cellular localization|| |
Nucleus / Chromosome / Chromosome > centromere
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St John’s Laboratory Ltd.
|Product type|| |
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