Mouse Monoclonal SCP-3 antibody (STJ98548)

$379.00

Reactivity: Human
Applications: WB
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Mouse Monoclonal SCP-3 antibody (STJ98548)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB

Recommended dilution: WB 1:1000-1:2000

Recommended protocols: check protocols

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Alternative names:

Check alternative names for the antibody

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SYCP3 antibody, SCP3 antibody,|choline phosphotransferase 1 antibody|chpt1 antibody|COR 1 antibody|COR1 antibody|MGC71888 antibody|RNASCP3 antibody|SCP 3 antibody|SCP-3 antibody|SCP3 antibody|SPGF4 antibody|Sycp 3 antibody|Sycp3 antibody|SYCP3_HUMAN antibody|Synaptonemal complex protein 3 antibody|Anti-SCP3 antibody (ab15093)
SCBT cat No: To be updated

 

Name

SCP-3 Monoclonal Antibody

Catalogue No.

STJ98548

Reactivity

Human

Specificity

SCP-3 Monoclonal Antibody detects endogenous levels of SCP-3 protein.

Immunogen

Purified recombinant human SCP-3 protein fragments expressed in Ecoli

Host

Mouse

Applications

WB

Recommended dilution

WB 1:1000-1:2000

Clonality

Monoclonal

Conjugation

Unconjugated

Formulation

SCP-3 Antibody was tube-contained. Purified in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol.

Concentration

1 mg/ml

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Synaptonemal complex protein 3 antibody, SCP-3 antibody

Database links

Human UniProt/Swiss-Prot:Q8IZU3;Mouse UniPort/Swiss-Prot: P70281;Rat UniProt/Swiss-Port: Q63520;Human Entrez Gene: 50511;Mouse Entrez Gene: 20962;Rat Entrez Gene: Rn.34889

Protein names

Synaptonemal complex protein 3 , SCP-3

Protein function

Component of the synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Required for centromere pairing during meiosis in male germ cells (By similarity). Required for normal meiosis during spermatogenesis and male fertility . Plays a lesser role in female fertility. Required for efficient phosphorylation of HORMAD1 and HORMAD2 (By similarity).

Protein tissue specificity

Testis-specific.

Involvement in disease

Spermatogenic failure 4 (SPGF4) [MIM:270960]: An infertility disorder characterized by azoospermia, a condition of having no sperm present in the ejaculate. Testicular histology shows arrest of spermatogenesis at the pachytene stage of primary spermatocytes. . Note: The disease is caused by mutations affecting the gene represented in this entry.; Pregnancy loss, recurrent, 4 (RPRGL4) [MIM:270960]: A common complication of pregnancy, resulting in spontaneous abortion before the fetus has reached viability. The term includes all miscarriages from the time of conception until 24 weeks of gestation. Recurrent pregnancy loss is defined as 3 or more consecutive spontaneous abortions. . Note: Disease susceptibility is associated with variations affecting the gene represented in this entry.

Protein sequence and domain

Composed of a long central coiled coil domain. The N-terminal and C-terminal regions interact with DNA. / Belongs to the XLR/SYCP3 family.

Protein post-translational modifications

Phosphorylated.

Protein cellular localization

Nucleus / Chromosome / Chromosome > centromere

Research area

All research areas>Cell Cycle Proteins>SCP
(View all antibody categories related to Cell Cycle Proteins)

Note

AntibodyPlus can customize SCP-3 Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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