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Mouse Monoclonal SmcX antibody (STJ98552)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, IF
Recommended dilution: WB 1:1000-1:2000; IF 1:100-1:500
Recommended protocols: check protocols
Click or hover above images to see image description for SmcX Monoclonal Antibody.
Check alternative names for the antibodyExpand
KDM5C antibody, DXS1272E antibody, JARID1C antibody, SMCX antibody, XE169 antibody,|DXS1272E antibody|Histone demethylase JARID1C antibody|JARID1C antibody|JmjC domain containing protein SMCX antibody|Jumonji AT rich interactive domain 1C antibody|Jumonji, AT rich interactive domain 1C (RBP2 like) antibody|Jumonji/ARID domain-containing protein 1C antibody|KDM5C antibody|KDM5C_HUMAN antibody|Lysine (K) specific demethylase 5C antibody|Lysine-specific demethylase 5C antibody|MRX13 antibody|MRXJ antibody|MRXSCJ antibody|MRXSJ antibody|Protein SmcX antibody|Protein Xe169 antibody|rbp2 like protein antibody|Selected cDNA on X antibody|SMCX antibody|Smcx homolog X chromosome antibody|SmcX protein antibody|Smcy homolog X linked antibody|XE169 antibody|Xe169 protein antibody|Anti-KDM5C / Jarid1C / SMCX antibody – ChIP Grade (ab34718)
SCBT cat No: To be updated
SmcX Monoclonal Antibody
|Catalogue No.|| |
Human, Mouse, Rat, Cow, Dog
SmcX Monoclonal Antibody detects endogenous levels of SmcX protein.
Purified recombinant human SmcX (C-terminus) protein fragments expressed in Ecoli
|Recommended dilution|| |
WB 1:1000-1:2000; IF 1:100-1:500
SmcX Antibody was tube-contained. Purified in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol.
SmcX Antibody was purified using affinity purification.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Lysine-specific demethylase 5C antibody, Histone demethylase JARID1C antibody, Jumonji/ARID domain-containing protein 1C antibody, Protein SmcX antibody, Protein Xe169 antibody
|Protein names|| |
Lysine-specific demethylase 5C , Histone demethylase JARID1C , Jumonji/ARID domain-containing protein 1C , Protein SmcX , Protein Xe169
|Protein function|| |
Histone demethylase that specifically demethylates ‘Lys-4’ of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 ‘Lys-9’, H3 ‘Lys-27’, H3 ‘Lys-36’, H3 ‘Lys-79’ or H4 ‘Lys-20’. Demethylates trimethylated and dimethylated but not monomethylated H3 ‘Lys-4’. Participates in transcriptional repression of neuronal genes by recruiting histone deacetylases and REST at neuron-restrictive silencer elements. Represses the CLOCK-ARNTL/BMAL1 heterodimer-mediated transcriptional activation of the core clock component PER2 (By similarity). / 2-oxoglutarate / Fe2+
|Protein tissue specificity|| |
Expressed in all tissues examined. Highest levels found in brain and skeletal muscle.
|Involvement in disease|| |
Mental retardation, X-linked, syndromic, Claes-Jensen type (MRXSCJ) [MIM:300534]: A disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period. MRXSCJ patients manifest mental retardation associated with variable features such as slowly progressive spastic paraplegia, seizures, facial dysmorphism. . Note: The disease is caused by mutations affecting the gene represented in this entry.
|Protein sequence and domain|| |
The first PHD-type zinc finger domain recognizes and binds H3-K9Me3. / Both the JmjC domain and the JmjN domain are required for enzymatic activity. / Belongs to the JARID1 histone demethylase family. / Contains 1 ARID domain. / Contains 1 JmjC domain. / Contains 1 JmjN domain. / Contains 2 PHD-type zinc fingers.
|Protein cellular localization|| |
AntibodyPlus can customize SmcX Antibody according to your requirement, including bulk product size,etc. Please contact firstname.lastname@example.org. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.
St John’s Laboratory Ltd.
|Product type|| |
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