Mouse Monoclonal SOX-2 antibody (STJ98555)


Reactivity: Human, Mouse, Rat, Cow, Pig, Sheep
Applications: WB
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Mouse Monoclonal SOX-2 antibody (STJ98555)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB

Recommended dilution: WB 1:1000-1:2000

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for SOX-2 Monoclonal Antibody.

Alternative names:

Check alternative names for the antibody


SOX2 antibody,|ANOP3 antibody|SRY-box 2 antibody|Transcription factor SOX 2 antibody|Transcription factor SOX-2 antibody|ysb antibody|Anti-SOX2 antibody (ab97959)
SCBT cat No: To be updated



SOX-2 Monoclonal Antibody

Catalogue No.



Human, Mouse, Rat, Cow, Pig, Sheep


SOX-2 Monoclonal Antibody detects endogenous levels of SOX-2 protein.


Purified recombinant human SOX-2 protein fragments expressed in Ecoli





Recommended dilution

WB 1:1000-1:2000






SOX-2 Antibody was tube-contained. Purified in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol.


1 mg/ml


SOX-2 Antibody was purified using affinity purification.


-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Transcription factor SOX-2 antibody

Database links

Human UniProt/Swiss-Prot:P48431;Mouse UniPort/Swiss-Prot: P48432;Rat UniProt/Swiss-Port: D4A543;Human Entrez Gene: 6657;Mouse Entrez Gene: 20674;Rat Entrez Gene: Rn.17369

Protein names

Transcription factor SOX-2

Protein function

Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity).

Involvement in disease

Microphthalmia, syndromic, 3 (MCOPS3) [MIM:206900]: A disease characterized by the rare association of malformations including uni- or bilateral anophthalmia or microphthalmia, and esophageal atresia with trachoesophageal fistula. Microphthalmia is a disorder of eye formation, ranging from small size of a single eye to complete bilateral absence of ocular tissues (anophthalmia). In many cases, microphthalmia/anophthalmia occurs in association with syndromes that include non-ocular abnormalities. . Note: The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Contains 1 HMG box DNA-binding domain.

Protein post-translational modifications

Sumoylation inhibits binding on DNA and negatively regulates the FGF4 transactivation.

Protein cellular localization


Research area

All research areas>Transcription Regulators>Sox-2
(View all antibody categories related to Transcription Regulators)


AntibodyPlus can customize SOX-2 Antibody according to your requirement, including bulk product size,etc. Please contact AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.


St John’s Laboratory Ltd.

Product type

Primary antibody


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