No products in the cart.
Mouse Monoclonal Stat5b antibody [5B3] (STJ98401)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, ELISA
Recommended dilution: WB 1:500-1:2000; ELISA 1:10000
Recommended protocols: check protocols
Click or hover above images to see image description for Stat5b Monoclonal Antibody.
Check alternative names for the antibodyExpand
STAT5B antibody,|Signal transducer and activator of transcription 5B antibody|STA5B_HUMAN antibody|STAT5 antibody|Stat5b antibody|Transcription factor STAT5B antibody|Anti-STAT5b [EPR16671] antibody (ab178941)
SCBT cat No: sc-81524|sc-12893|sc-101806|sc-81525|sc-136019|sc-101808|sc-11762|
Stat5b Monoclonal Antibody
|Catalogue No.|| |
Stat5b Monoclonal Antibody detects endogenous levels of Stat5b protein.
Purified recombinant fragment of human Stat5b expressed in E Coli
|Recommended dilution|| |
WB 1:500-1:2000; ELISA 1:10000
Stat5b Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.
Stat5b Antibody was purified using affinity purification.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Signal transducer and activator of transcription 5B antibody
|Protein names|| |
Signal transducer and activator of transcription 5B
|Protein function|| |
Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Binds to the GAS element and activates PRL-induced transcription.
|Involvement in disease|| |
Growth hormone insensitivity with immunodeficiency (GHII) [MIM:245590]: A disease characterized by short stature, growth hormone deficiency in the presence of normal to elevated circulating concentrations of growth hormone, resistance to hexogeneous growth hormone therapy, and recurrent infections. . Note: The disease is caused by mutations affecting the gene represented in this entry.
|Protein sequence and domain|| |
Belongs to the transcription factor STAT family. / Contains 1 SH2 domain.
|Protein post-translational modifications|| |
Tyrosine phosphorylated in response to signaling via activated KIT, resulting in translocation to the nucleus. Tyrosine phosphorylated in response to signaling via activated FLT3; wild-type FLT3 results in much weaker phosphorylation than constitutively activated mutant FLT3. Alternatively, can be phosphorylated by JAK2. Phosphorylation at Tyr-699 by PTK6 or HCK leads to an increase of its transcriptional activity. Dephosphorylation on tyrosine residues by PTPN2 negatively regulates prolactin signaling pathway.
|Protein cellular localization|| |
Cytoplasm / Nucleus
AntibodyPlus can customize Stat5b Antibody according to your requirement, including bulk product size,etc. Please contact firstname.lastname@example.org. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.
St John’s Laboratory Ltd.
|Product type|| |
There are no reviews for this product yet.
By submitting a review, get following benefits:
1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!
There is no extra validation for this product yet.
Check other extra validated antibodies below: