Mouse Monoclonal SYK antibody [8C1A3] (STJ98406)


Reactivity: Human
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Mouse Monoclonal SYK antibody [8C1A3] (STJ98406)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-1:2000; ELISA 1:10000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody


SLC22A1 antibody, OCT1 antibody,|hOCT1 antibody|OCT1 antibody|oct1_cds antibody|Organic cation transporter 1 antibody|S22A1_HUMAN antibody|Slc22a1 antibody|solute carrier family 22 (organic cation transporter), member 1 antibody|Solute carrier family 22 member 1 antibody|Anti-SLC22A1 antibody (ab55916)
SCBT cat No: sc-293181|sc-232|sc-28334|



SYK Monoclonal Antibody

Catalogue No.





SYK Monoclonal Antibody detects endogenous levels of SYK protein.


Purified recombinant fragment of SYK (aa296-484) expressed in E Coli





Recommended dilution

WB 1:500-1:2000; ELISA 1:10000








SYK Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.


1 mg/ml


SYK Antibody was purified using affinity purification.


-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Solute carrier family 22 member 1 antibody, Organic cation transporter 1 antibody, hOCT1 antibody

Database links

Human UniProt/Swiss-Prot:O15245;Mouse UniPort/Swiss-Prot: O08966;Rat UniProt/Swiss-Port: Q63089;Human Entrez Gene: 6580;Mouse Entrez Gene: 20517;Rat Entrez Gene: Rn.11186

Protein names

Solute carrier family 22 member 1 , Organic cation transporter 1 , hOCT1

Protein function

Translocates a broad array of organic cations with various structures and molecular weights including the model compounds 1-methyl-4-phenylpyridinium (MPP), tetraethylammonium (TEA), N-1-methylnicotinamide (NMN), 4-(4-(dimethylamino)styryl)-N-methylpyridinium (ASP), the endogenous compounds choline, guanidine, histamine, epinephrine, adrenaline, noradrenaline and dopamine, and the drugs quinine, and metformin. The transport of organic cations is inhibited by a broad array of compounds like tetramethylammonium (TMA), cocaine, lidocaine, NMDA receptor antagonists, atropine, prazosin, cimetidine, TEA and NMN, guanidine, cimetidine, choline, procainamide, quinine, tetrabutylammonium, and tetrapentylammonium. Translocates organic cations in an electrogenic and pH-independent manner. Translocates organic cations across the plasma membrane in both directions. Transports the polyamines spermine and spermidine. Transports pramipexole across the basolateral membrane of the proximal tubular epithelial cells. The choline transport is activated by MMTS. Regulated by various intracellular signaling pathways including inhibition by protein kinase A activation, and endogenously activation by the calmodulin complex, the calmodulin-dependent kinase II and LCK tyrosine kinase. / 1.47 mM for metformin / 229 µM for TEA / 14.6 µM for MPP / 396 pmol/min/mg enzyme for metformin uptake / 2.89 nmol/min/mg enzyme for TEA uptake

Protein tissue specificity

Widely expressed with high level in liver. Isoform 1 and isoform 2 are expressed in liver. Isoform 1, isoform 2, isoform 3 and isoform 4 are expressed in glial cell lines.

Protein sequence and domain

Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family. [View classification]

Protein post-translational modifications


Protein cellular localization

Basolateral cell membrane / Multi-pass membrane protein

Research area

All research areas>Kinases and Phosphatases>Syk
(View all antibody categories related to Kinases and Phosphatases)


AntibodyPlus can customize SYK Antibody according to your requirement, including bulk product size,etc. Please contact AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.


St John’s Laboratory Ltd.

Product type

Primary antibody


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