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Mouse Monoclonal SYP antibody [7H12] (STJ98410)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, IHC, ELISA
Recommended dilution: WB 1:500-1:2000; IHC 1:200-1:1000; ELISA 1:10000
Recommended protocols: check protocols
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Check alternative names for the antibodyExpand
SYP antibody,|Major synaptic vesicle protein p38 antibody|MRX96 antibody|MRXSYP antibody|Syn p38 antibody|Synaptophysin antibody|Syp antibody|SYPH antibody|SYPH_HUMAN antibody|SypI antibody|Anti-Synaptophysin antibody [YE269] (ab32127)
SCBT cat No: sc-130606|sc-30037|sc-18205|sc-130219|sc-248320|sc-71794|sc-32275|sc-32276|sc-12413|sc-101812|sc-32828|
SYP Monoclonal Antibody
|Catalogue No.|| |
SYP Monoclonal Antibody detects endogenous levels of SYP protein.
Purified recombinant fragment of SYP expressed in E Coli
WB, IHC, ELISA
|Recommended dilution|| |
WB 1:500-1:2000; IHC 1:200-1:1000; ELISA 1:10000
SYP Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.
SYP Antibody was purified using affinity purification.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Synaptophysin antibody, Major synaptic vesicle protein p38 antibody
|Protein names|| |
Synaptophysin , Major synaptic vesicle protein p38
|Protein function|| |
Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity (By similarity).
|Protein tissue specificity|| |
Characteristic of a type of small (30-80 nm) neurosecretory vesicles, including presynaptic vesicles, but also vesicles of various neuroendocrine cells of both neuronal and epithelial phenotype.
|Involvement in disease|| |
Mental retardation, X-linked, SYP-related (MRXSYP) [MIM:300802]: A disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period. . Note: The disease is caused by mutations affecting the gene represented in this entry.
|Protein sequence and domain|| |
The calcium-binding activity is thought to be localized in the cytoplasmic tail of the protein. / Belongs to the synaptophysin/synaptobrevin family. / Contains 1 MARVEL domain.
|Protein post-translational modifications|| |
Ubiquitinated; mediated by SIAH1 or SIAH2 and leading to its subsequent proteasomal degradation.
|Protein cellular localization|| |
Cytoplasmic vesicle > secretory vesicle > synaptic vesicle membrane; Multi-pass membrane protein / Cell junction > synapse > synaptosome
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St John’s Laboratory Ltd.
|Product type|| |
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