Mouse Monoclonal TBX5 antibody [7B11] (STJ98413)

$379.00

Reactivity: Human
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Mouse Monoclonal TBX5 antibody [7B11] (STJ98413)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-1:2000; ELISA 1:10000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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TBX5 antibody,|Holt Oram syndrome antibody|HOS antibody|T box 5 antibody|T box protein 5 antibody|T box transcription factor TBX 5 antibody|T box transcription factor TBX5 antibody|T-box protein 5 antibody|T-box transcription factor TBX5 antibody|TBX 5 antibody|TBX5 antibody|TBX5_HUMAN antibody|Transcription factor T box 5 antibody|Anti-TBX5 antibody (ab137833)
SCBT cat No: To be updated

 

Name

TBX5 Monoclonal Antibody

Catalogue No.

STJ98413

Reactivity

Human

Specificity

TBX5 Monoclonal Antibody detects endogenous levels of TBX5 protein.

Immunogen

Purified recombinant fragment of TBX5 expressed in E Coli

Host

Mouse

Applications

WB, ELISA

Recommended dilution

WB 1:500-1:2000; ELISA 1:10000

Clonality

Monoclonal

Conjugation

Unconjugated

Isotype

IgG1

Formulation

TBX5 Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.

Concentration

1 mg/ml

Purification

TBX5 Antibody was purified using affinity purification.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

T-box transcription factor TBX5 antibody, T-box protein 5 antibody

Database links

Human UniProt/Swiss-Prot:Q99593;Mouse UniPort/Swiss-Prot: P70326;Rat UniProt/Swiss-Port: Q5I2P1;Human Entrez Gene: 6910;Mouse Entrez Gene: 21388;Rat Entrez Gene: Rn.6327

Protein names

T-box transcription factor TBX5 , T-box protein 5

Protein function

DNA-binding protein that regulates the transcription of several genes and is involved in heart development and limb pattern formation.

Involvement in disease

Holt-Oram syndrome (HOS) [MIM:142900]: Developmental disorder affecting the heart and upper limbs. It is characterized by thumb anomaly and atrial septal defects. . Note: The disease is caused by mutations affecting the gene represented in this entry.; Note: Defects in TBX5 are associated with susceptibility to heart disorders including dilated cardiomyopathy (DCM) and atrial fibrillation (AF). DCM is characterized by ventricular and impaired systolic function, resulting in heart failure and arrhythmia. Patient are at risk of premature death. AF is a common sustained cardiac rhythm disturbance. AF is characterized by disorganized atrial electrical activity and ineffective atrial contraction promoting blood stasis in the atria and reduces ventricular filling. It can result in palpitations, syncope, thromboembolic stroke, and congestive heart failure. .

Protein sequence and domain

Contains 1 T-box DNA-binding domain.

Protein cellular localization

Nucleus

Research area

All research areas>Transcription Regulators>TBX
(View all antibody categories related to Transcription Regulators)

Note

AntibodyPlus can customize TBX5 Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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