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Mouse Monoclonal TBX5 antibody [7B11] (STJ98413)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, ELISA
Recommended dilution: WB 1:500-1:2000; ELISA 1:10000
Recommended protocols: check protocols
Click or hover above images to see image description for TBX5 Monoclonal Antibody.
Check alternative names for the antibodyExpand
TBX5 antibody,|Holt Oram syndrome antibody|HOS antibody|T box 5 antibody|T box protein 5 antibody|T box transcription factor TBX 5 antibody|T box transcription factor TBX5 antibody|T-box protein 5 antibody|T-box transcription factor TBX5 antibody|TBX 5 antibody|TBX5 antibody|TBX5_HUMAN antibody|Transcription factor T box 5 antibody|Anti-TBX5 antibody (ab137833)
SCBT cat No: To be updated
TBX5 Monoclonal Antibody
|Catalogue No.|| |
TBX5 Monoclonal Antibody detects endogenous levels of TBX5 protein.
Purified recombinant fragment of TBX5 expressed in E Coli
|Recommended dilution|| |
WB 1:500-1:2000; ELISA 1:10000
TBX5 Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.
TBX5 Antibody was purified using affinity purification.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
T-box transcription factor TBX5 antibody, T-box protein 5 antibody
|Protein names|| |
T-box transcription factor TBX5 , T-box protein 5
|Protein function|| |
DNA-binding protein that regulates the transcription of several genes and is involved in heart development and limb pattern formation.
|Involvement in disease|| |
Holt-Oram syndrome (HOS) [MIM:142900]: Developmental disorder affecting the heart and upper limbs. It is characterized by thumb anomaly and atrial septal defects. . Note: The disease is caused by mutations affecting the gene represented in this entry.; Note: Defects in TBX5 are associated with susceptibility to heart disorders including dilated cardiomyopathy (DCM) and atrial fibrillation (AF). DCM is characterized by ventricular and impaired systolic function, resulting in heart failure and arrhythmia. Patient are at risk of premature death. AF is a common sustained cardiac rhythm disturbance. AF is characterized by disorganized atrial electrical activity and ineffective atrial contraction promoting blood stasis in the atria and reduces ventricular filling. It can result in palpitations, syncope, thromboembolic stroke, and congestive heart failure. .
|Protein sequence and domain|| |
Contains 1 T-box DNA-binding domain.
|Protein cellular localization|| |
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St John’s Laboratory Ltd.
|Product type|| |
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