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Mouse Monoclonal Thioredoxin antibody [1H6H6] (STJ98420)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, ELISA
Recommended dilution: WB 1:500-1:2000; ELISA 1:10000
Recommended protocols: check protocols
Click or hover above images to see image description for Thioredoxin Monoclonal Antibody.
Check alternative names for the antibodyExpand
TXN antibody, TRDX antibody, TRX antibody, TRX1 antibody,|ADF antibody|ATL derived factor antibody|ATL-derived factor antibody|DKFZp686B1993 antibody|MGC61975 antibody|SASP antibody|Surface associated sulphydryl protein antibody|Surface-associated sulphydryl protein antibody|testicular tissue protein Li 199 antibody|THIO_HUMAN antibody|Thioredoxin antibody|thioredoxin delta 3 antibody|TRDX antibody|TRX 1 antibody|Trx antibody|TRX1 antibody|TXN antibody|TXN delta 3 antibody|TXN protein antibody|zgc:92903 antibody|Anti-Thioredoxin / TRX antibody (ab26320)
SCBT cat No: To be updated
Thioredoxin Monoclonal Antibody
|Catalogue No.|| |
Thioredoxin Monoclonal Antibody detects endogenous levels of Thioredoxin protein.
Purified recombinant fusion protein with Thioredoxin tag
|Recommended dilution|| |
WB 1:500-1:2000; ELISA 1:10000
Thioredoxin Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.
Thioredoxin Antibody was purified using affinity purification.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Thioredoxin antibody, Trx antibody, ATL-derived factor antibody, ADF antibody, Surface-associated sulphydryl protein antibody, SASP antibody
|Protein names|| |
Thioredoxin , Trx , ATL-derived factor , ADF , Surface-associated sulphydryl protein , SASP
|Protein function|| |
Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity. / ADF augments the expression of the interleukin-2 receptor TAC (IL2R/P55).
|Protein tissue specificity|| |
Up-regulated by ionizing radiation.
|Protein sequence and domain|| |
Belongs to the thioredoxin family. / Contains 1 thioredoxin domain.
|Protein post-translational modifications|| |
In the fully reduced protein, both Cys-69 and Cys-73 are nitrosylated in response to nitric oxide (NO). When two disulfide bonds are present in the protein, only Cys-73 is nitrosylated. Cys-73 can serve as donor for nitrosylation of target proteins. / In case of infection, ubiquitinated by S.typhimurium protein slrP, leading to its degradation.
|Protein cellular localization|| |
Nucleus / Cytoplasm / Secreted
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St John’s Laboratory Ltd.
|Product type|| |
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