Mouse Monoclonal Thioredoxin antibody [1H6H6] (STJ98420)

$379.00

Reactivity: Human
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Mouse Monoclonal Thioredoxin antibody [1H6H6] (STJ98420)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-1:2000; ELISA 1:10000

Recommended protocols: check protocols

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Alternative names:

Check alternative names for the antibody

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TXN antibody, TRDX antibody, TRX antibody, TRX1 antibody,|ADF antibody|ATL derived factor antibody|ATL-derived factor antibody|DKFZp686B1993 antibody|MGC61975 antibody|SASP antibody|Surface associated sulphydryl protein antibody|Surface-associated sulphydryl protein antibody|testicular tissue protein Li 199 antibody|THIO_HUMAN antibody|Thioredoxin antibody|thioredoxin delta 3 antibody|TRDX antibody|TRX 1 antibody|Trx antibody|TRX1 antibody|TXN antibody|TXN delta 3 antibody|TXN protein antibody|zgc:92903 antibody|Anti-Thioredoxin / TRX antibody (ab26320)
SCBT cat No: To be updated

 

Name

Thioredoxin Monoclonal Antibody

Catalogue No.

STJ98420

Reactivity

Human

Specificity

Thioredoxin Monoclonal Antibody detects endogenous levels of Thioredoxin protein.

Immunogen

Purified recombinant fusion protein with Thioredoxin tag

Host

Mouse

Applications

WB, ELISA

Recommended dilution

WB 1:500-1:2000; ELISA 1:10000

Clonality

Monoclonal

Conjugation

Unconjugated

Isotype

IgG1

Formulation

Thioredoxin Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.

Concentration

1 mg/ml

Purification

Thioredoxin Antibody was purified using affinity purification.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Thioredoxin antibody, Trx antibody, ATL-derived factor antibody, ADF antibody, Surface-associated sulphydryl protein antibody, SASP antibody

Database links

Human UniProt/Swiss-Prot:P10599;Mouse UniPort/Swiss-Prot: P10639;Rat UniProt/Swiss-Port: P11232;Human Entrez Gene: 7295;Mouse Entrez Gene: 22166;Rat Entrez Gene: Rn.29777

Protein names

Thioredoxin , Trx , ATL-derived factor , ADF , Surface-associated sulphydryl protein , SASP

Protein function

Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity. / ADF augments the expression of the interleukin-2 receptor TAC (IL2R/P55).

Protein tissue specificity

Up-regulated by ionizing radiation.

Protein sequence and domain

Belongs to the thioredoxin family. / Contains 1 thioredoxin domain.

Protein post-translational modifications

In the fully reduced protein, both Cys-69 and Cys-73 are nitrosylated in response to nitric oxide (NO). When two disulfide bonds are present in the protein, only Cys-73 is nitrosylated. Cys-73 can serve as donor for nitrosylation of target proteins. / In case of infection, ubiquitinated by S.typhimurium protein slrP, leading to its degradation.

Protein cellular localization

Nucleus / Cytoplasm / Secreted

Research area

All research areas>Synthesis and Degradation>Trx
(View all antibody categories related to Synthesis and Degradation)

Note

AntibodyPlus can customize Thioredoxin Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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