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Mouse Monoclonal TORC3 antibody [5G9] (STJ98428)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, IHC, IF, ELISA
Recommended dilution: WB 1:500-1:2000; IHC 1:200-1:1000; IF 1:200-1:1000; ELISA 1:10000
Recommended protocols: check protocols
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Check alternative names for the antibodyExpand
CRTC3 antibody, TORC3 antibody,|CREB regulated transcription coactivator 3 antibody|CREB-regulated transcription coactivator 3 antibody|CRTC 3 antibody|CRTC3 antibody|CRTC3_HUMAN antibody|FLJ21868 antibody|TORC 3 antibody|TORC-3 antibody|TORC3 antibody|Transducer of CREB protein 3 antibody|Transducer of regulated cAMP response element binding protein (CREB) 3 antibody|Transducer of regulated cAMP response element binding protein 3 antibody|Transducer of regulated cAMP response element-binding protein 3 antibody|Transducer of regulated CREB protein 3 antibody|Anti-CRTC3 antibody [EPR3440] (ab91654)
SCBT cat No: To be updated
TORC3 Monoclonal Antibody
|Catalogue No.|| |
TORC3 Monoclonal Antibody detects endogenous levels of TORC3 protein.
Purified recombinant fragment of human TORC3 expressed in E Coli
WB, IHC, IF, ELISA
|Recommended dilution|| |
WB 1:500-1:2000; IHC 1:200-1:1000; IF 1:200-1:1000; ELISA 1:10000
TORC3 Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.
TORC3 Antibody was purified using affinity purification.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
CREB-regulated transcription coactivator 3 antibody, Transducer of regulated cAMP response element-binding protein 3 antibody, TORC-3 antibody, Transducer of CREB protein 3 antibody
|Protein names|| |
CREB-regulated transcription coactivator 3 , Transducer of regulated cAMP response element-binding protein 3 , TORC-3 , Transducer of CREB protein 3
|Protein function|| |
Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 ‘Ser-133’ phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR).
|Protein tissue specificity|| |
Predominantly expressed in B and T lymphocytes. Highest levels in lung. Also expressed in brain, colon, heart, kidney, ovary, and prostate. Weak expression in liver, pancreas, muscle, small intestine, spleen and stomach.
|Protein sequence and domain|| |
Belongs to the TORC family.
|Protein cellular localization|| |
Nucleus / Cytoplasm
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St John’s Laboratory Ltd.
|Product type|| |
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