Mouse Monoclonal Wnt-10b antibody [5A7] (STJ98452)

$379.00

Reactivity: Human
Applications: WB, IHC, IF, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Mouse Monoclonal Wnt-10b antibody [5A7] (STJ98452)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IHC, IF, ELISA

Recommended dilution: WB 1:500-1:2000; IHC 1:200-1:1000; IF 1:200-1:1000; ELISA 1:10000

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Wnt-10b Monoclonal Antibody.

Alternative names:

Check alternative names for the antibody

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WNT10B antibody, WNT12 antibody,|Protein Wnt-10b antibody|Protein Wnt-12 antibody|SHFM6 antibody|wingless type MMTV integration site family, member 10B antibody|WN10B_HUMAN antibody|WNT 10B protein antibody|WNT 12 antibody|Wnt10b antibody|wnt12 antibody|Anti-Wnt10b antibody (ab70816)
SCBT cat No: To be updated

 

Name

Wnt-10b Monoclonal Antibody

Catalogue No.

STJ98452

Reactivity

Human

Specificity

Wnt-10b Monoclonal Antibody detects endogenous levels of Wnt-10b protein.

Immunogen

Purified recombinant fragment of human Wnt-10b expressed in E Coli

Host

Mouse

Applications

WB, IHC, IF, ELISA

Recommended dilution

WB 1:500-1:2000; IHC 1:200-1:1000; IF 1:200-1:1000; ELISA 1:10000

Clonality

Monoclonal

Conjugation

Unconjugated

Isotype

IgG1

Formulation

Wnt-10b Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.

Concentration

1 mg/ml

Purification

Wnt-10b Antibody was purified using affinity purification.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Protein Wnt-10b antibody, Protein Wnt-12 antibody

Database links

Human UniProt/Swiss-Prot:O00744;Mouse UniPort/Swiss-Prot: P48614;Rat UniProt/Swiss-Port: A0A0G2K6Q8;Human Entrez Gene: 7480;Mouse Entrez Gene: 22410;Rat Entrez Gene: Rn.218544

Protein names

Protein Wnt-10b , Protein Wnt-12

Protein function

Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters (By similarity).

Protein tissue specificity

Detected in most adult tissues. Highest levels were found in heart and skeletal muscle. Low levels are found in brain.

Involvement in disease

Split-hand/foot malformation 6 (SHFM6) [MIM:225300]: A limb malformation involving the central rays of the autopod and presenting with syndactyly, median clefts of the hands and feet, and aplasia and/or hypoplasia of the phalanges, metacarpals, and metatarsals. Some patients have been found to have mental retardation, ectodermal and craniofacial findings, and orofacial clefting. . Note: The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the Wnt family.

Protein post-translational modifications

Palmitoleylation is required for efficient binding to frizzled receptors. Depalmitoleylation leads to Wnt signaling pathway inhibition.

Protein cellular localization

Secreted > extracellular space > extracellular matrix

Research area

All research areas>Signaling Intermediates>Wnt-10b
(View all antibody categories related to Signaling Intermediates)

Note

AntibodyPlus can customize Wnt-10b Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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