Mouse sRANK Ligand / TNFSF11 / TRANCE ELISA Kit (ARG80222)

$499.00

Size: 96 wells
Conjugation: HRP
Supplier: Arigo Biolaboratories

Overview


Supplier : Arigo Biolaboratories

 Production type ELISA Kits
Tested Reactivity Mouse
Tested Application ELISA
Specificity No significant cross-reactivity or interference with Mouse C10 MIP-1, JE MIP-1 , KC;human GRO beta, GRO gamma, RANTES
Target Name sRANK Ligand / TNFSF11 / TRANCE
Conjugation HRP
Conjugation Note Substrate: TMB and read at 450 nm
Sensitivity 15 pg/ml
Detection Range 31.25-2000 pg/ml
Sample Type Serum, Plasma, Cell culture supernatants
Sample Volume 100 ul
Precision

CV: <10%

Full Name tumor necrosis factor (ligand) superfamily, member 11
Alternate Names Check alternative names for the Mouse sRANK Ligand / TNFSF11 / TRANCE ELISA Kit

Expand

CD254 Elisa kits|TNF11_HUMAN Elisa kits|TNFSF 11 Elisa kits|Tnfsf11 Elisa kits|TRANCE Elisa kits|Tumor necrosis factor (ligand) superfamily member 11 Elisa kits|Tumor necrosis factor ligand superfamily member 11 Elisa kits|Tumor necrosis factor ligand superfamily member 11, soluble form Elisa kits


Application Instructions

 

Assay Time 4 hours


Properties

 

Form 96 wells
Storage instruction Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components or simply ask Antibodyplus for ELISA troublesooting.
Note Antibodyplus and Arigo provide the most validated ELISA kits for researchers. For laboratory research only, not for drug, diagnostic or other use.
User’s manual of Mouse sRANK Ligand / TNFSF11 / TRANCE ELISA Kit  Download
size

96 wells

Cat No.

ARG80222

Conjugation note

Substrate: TMB and read at 450 nm

Sensitivity

15 pg/ml

Detection range

31.25-2000 pg/ml

Sample type

Serum, Plasma, Cell culture supernatants

Sample Volume

100 ul

Precision

CV: <10%

Target name

sRANK Ligand / TNFSF11 / TRANCE

Assay time

4 hours

Store at

4 Celcius degree

Storage instruction

Store the kit at 2-8 Celcius degree. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.

Background

This gene encodes a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. This protein was shown to be a dentritic cell survival factor and is involved in the regulation of T cell-dependent immune response. T cell activation was reported to induce expression of this gene and lead to an increase of osteoclastogenesis and bone loss. This protein was shown to activate antiapoptotic kinase AKT/PKB through a signaling complex involving SRC kinase and tumor necrosis factor receptor-associated factor (TRAF) 6, which indicated this protein may have a role in the regulation of cell apoptosis. Targeted disruption of the related gene in mice led to severe osteopetrosis and a lack of osteoclasts. The deficient mice exhibited defects in early differentiation of T and B lymphocytes, and failed to form lobulo-alveolar mammary structures during pregnancy. Two alternatively spliced tra

Database link

All research areas>Lymphocyte Signaling>RANK
(View all antibody categories related to Lymphocyte Signaling)

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