Mouse/Rat beta-Amyloid (1 – 42) ELISA Kit (ARG80939)

$999.00

Size: 96 wells
Conjugation:
Supplier: Arigo Biolaboratories

Overview


Supplier : Arigo Biolaboratories

 Production type ELISA Kits
Tested Reactivity Mouse, Rat
Tested Application ELISA
Specificity
Target Name beta-Amyloid 1 – 42
Conjugation
Conjugation Note
Sensitivity 2 pg/ml (9 fmoles/ml) in brain lysate.
Detection Range
Sample Type Cell and tissue lysate as well as in body fluids.
Sample Volume 100 ul
Precision

CV: <10%

Full Name amyloid beta (A4) precursor protein
Alternate Names Check alternative names for the Mouse/Rat beta-Amyloid (1 – 42) ELISA Kit

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Application Instructions

 

Assay Time 1 h (RT)


Properties

 

Form 96 wells
Storage instruction Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components or simply ask Antibodyplus for ELISA troublesooting.
Note Antibodyplus and Arigo provide the most validated ELISA kits for researchers. For laboratory research only, not for drug, diagnostic or other use.
User’s manual of Mouse/Rat beta-Amyloid (1 – 42) ELISA Kit  Download
size

96 wells

Cat No.

ARG80939

Sensitivity

2 pg/ml (9 fmoles/ml) in brain lysate.

Sample type

Cell and tissue lysate as well as in body fluids.

Sample Volume

100 ul

Precision

CV: <10%

Target name

beta-Amyloid 1 – 42

Assay time

1 h (RT)

Store at

4 Celcius degree

Storage instruction

Store the kit at 2-8 Celcius degree. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.

Background

Alzheimer’s Disease (AD) is the most common neurodegenerative disorder in elderly people. It has been demonstrated that AD has biological causes and is characterized by the presence of senile plaques and neurofibrillary tangles mainly in cerebral cortex and hippocampus brain regions. Beta-Amyloid (1-40) (Abeta40) and beta-Amyloid (1-42) (Abeta42) are the main components of the above plaques; however, other forms of beta-Amyloid peptides are also present. Both peptides are cleaved from the Amyloid Precursor Protein (APP) by beta-secretase and gamma-secretase enzymes. Many studies suggest that Abeta42 or/and Abeta43 are required to initiate formation of amyloid plaques and neurofibrills that leads to the neurodegeneration, while Abeta40 is less neurotoxic.

Database link

All research areas>Neurobiology Antibodies>Amyloid
(View all antibody categories related to Neurobiology Antibodies)

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