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Supplier : Arigo Biolaboratories
|Production type||ELISA Kits|
|Tested Reactivity||Mouse, Rat|
|Target Name||beta-Amyloid 1 – 42|
|Sensitivity||2 pg/ml (9 fmoles/ml) in brain lysate.|
|Sample Type||Cell and tissue lysate as well as in body fluids.|
|Sample Volume||100 ul|
|Full Name||amyloid beta (A4) precursor protein|
|Alternate Names||Check alternative names for the Mouse/Rat beta-Amyloid (1 – 42) ELISA Kit Expand
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|Assay Time||1 h (RT)|
|Storage instruction||Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components or simply ask Antibodyplus for ELISA troublesooting.|
|Note||Antibodyplus and Arigo provide the most validated ELISA kits for researchers. For laboratory research only, not for drug, diagnostic or other use.|
|User’s manual of Mouse/Rat beta-Amyloid (1 – 42) ELISA Kit||Download|
|Cat No.|| |
2 pg/ml (9 fmoles/ml) in brain lysate.
|Sample type|| |
Cell and tissue lysate as well as in body fluids.
|Sample Volume|| |
|Target name|| |
beta-Amyloid 1 – 42
|Assay time|| |
1 h (RT)
|Store at|| |
4 Celcius degree
|Storage instruction|| |
Store the kit at 2-8 Celcius degree. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
Alzheimer’s Disease (AD) is the most common neurodegenerative disorder in elderly people. It has been demonstrated that AD has biological causes and is characterized by the presence of senile plaques and neurofibrillary tangles mainly in cerebral cortex and hippocampus brain regions. Beta-Amyloid (1-40) (Abeta40) and beta-Amyloid (1-42) (Abeta42) are the main components of the above plaques; however, other forms of beta-Amyloid peptides are also present. Both peptides are cleaved from the Amyloid Precursor Protein (APP) by beta-secretase and gamma-secretase enzymes. Many studies suggest that Abeta42 or/and Abeta43 are required to initiate formation of amyloid plaques and neurofibrills that leads to the neurodegeneration, while Abeta40 is less neurotoxic.
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