Rabbit polyclonal ABCC2 antibody (A8405)

$69.00$259.00

Reactivity: Human
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal ABCC2 antibody (A8405)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:500 – 1:2000

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal ABCC2 antibody.

Alternative names:

Check alternative names for the antibody

Expand

DJS antibody, MRP2 antibody, cMRP antibody, ABC30 antibody, CMOAT antibody
ABC30 antibody|abcC2 antibody|ATP binding cassette sub family C (CFTR/MRP) member 2 antibody|ATP binding cassette subfamily C member 2 antibody|ATP-binding cassette sub-family C member 2 antibody|Canalicular multidrug resistance protein antibody|Canalicular multispecific organic anion transporter 1 antibody|CMOAT antibody|CMOAT1 antibody|cMRP antibody|DJS antibody|KIAA1010 antibody|MRP 2 antibody|MRP2_HUMAN antibody|Multidrug resistance associated protein 2 antibody|Multidrug resistance-associated protein 2 antibody|Anti-MRP2 antibody [M2 III-6] (ab3373)

SCBT cat No: sc-71603|sc-5770|sc-20766|sc-59608|sc-59609|sc-59611|

Name

Rabbit polyclonal ABCC2 antibody

Catalogue No.

A8405

Reactivity

Human

Immunogen

Recombinant protein of human ABCC2

Host

Rabbit

Applications

WB

Recommended dilution

WB 1:500 – 1:2000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 174kDa/Observed: Refer to figures

Formulation

ABCC2 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

ABCC2 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

DJS antibody, MRP2 antibody, cMRP antibody, ABC30 antibody, CMOAT antibody

Database links

Human UniProt/Swiss-Prot:Q92887

Protein names

DJS, MRP2, cMRP, ABC30, CMOAT

Protein function

Mediates hepatobiliary excretion of numerous organic anions. May function as a cellular cisplatin transporter.

Protein tissue specificity

Expressed by polarized cells in liver, kidney and intestine. The highest expression is found in liver.

Protein sequence and domain

Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.; Contains 2 ABC transmembrane type-1 domains.; Contains 2 ABC transporter domains.

Protein cellular localization

Apical cell membrane ; Multi-pass membrane protein .

Background

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is expressed in the canalicular (apical) part of the hepatocyte and functions in biliary transport. Substrates include anticancer drugs such as vinblastine; therefore, this protein appears to contribute to drug resistance in mammalian cells. Several different mutations in this gene have been observed in patients with Dubin-Johnson syndrome (DJS), an autosomal recessive disorder characterized by conjugated hyperbilirubinemia.

Research area

All research areas>Signaling Intermediates>MRP
(View all antibody categories related to Signaling Intermediates)

Note

AntibodyPlus can customize ABCC2 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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