Rabbit Polyclonal ABCG2 antibody (STJ97253)

$99.00$319.00

Reactivity: Human
Applications: WB, IF
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal ABCG2 antibody (STJ97253)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IHC, ELISA

Recommended dilution: WB 1:500-1:2000; IHC-P 1:100-1:300; ELISA 1:10000;

Recommended protocols: check protocols

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Alternative names:

Check alternative names for the antibody

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ABCG2 antibody, ABCP antibody, BCRP antibody, BCRP1 antibody, MXR antibody,|ABC transporter antibody|ABC15 antibody|ABCG 2 antibody|ABCG2 antibody|ABCG2_HUMAN antibody|ABCP antibody|ATP binding cassette sub family G (WHITE) member 2 antibody|ATP binding cassette transporter G2 antibody|ATP-binding cassette sub-family G member 2 antibody|BCRP antibody|BCRP1 antibody|BMDP antibody|Breast cancer resistance protein antibody|CD338 antibody|CDw338 antibody|CDw338 antigen antibody|EST157481 antibody|GOUT1 antibody|MGC102821 antibody|Mitoxantrone resistance associated protein antibody|Mitoxantrone resistance-associated protein antibody|MRX antibody|Multi drug resistance efflux transport ATP binding cassette sub family G (WHITE) member 2 antibody|MXR antibody|MXR1 antibody|Placenta specific ATP binding cassette transporter antibody|Placenta specific MDR protein antibody|Placenta-specific ATP-binding cassette transporter antibody|UAQTL1 antibody|Anti-BCRP/ABCG2 antibody [BXP-53] (ab24115)
SCBT cat No: sc-25156|sc-25821|

Name

ABCG2 Polyclonal Antibody

Catalogue No.

STJ97253

Reactivity

Human

Specificity

ABCG2 Polyclonal Antibody detects endogenous levels of ABCG2 protein.

Immunogen

Synthesized peptide derived from ABCG2 at AA range 461-510

Host

Rabbit

Applications

WB, IHC, ELISA

Recommended dilution

WB 1:500-1:2000; IHC-P 1:100-1:300; ELISA 1:10000;

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Formulation

ABCG2 Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

ABCG2 Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

ATP-binding cassette sub-family G member 2 antibody, Breast cancer resistance protein antibody, CDw338 antibody, Mitoxantrone resistance-associated protein antibody, Placenta-specific ATP-binding cassette transporter antibody, Urate exporter antibody, CD antigen CD338 antibody

Database links

Human UniProt/Swiss-Prot:Q9UNQ0;Mouse UniPort/Swiss-Prot: Q7TMS5;Rat UniProt/Swiss-Port: Q80W57;Human Entrez Gene: 9429;Mouse Entrez Gene: 26357;Rat Entrez Gene: Rn.13131

Protein names

ATP-binding cassette sub-family G member 2 , Breast cancer resistance protein , CDw338 , Mitoxantrone resistance-associated protein , Placenta-specific ATP-binding cassette transporter , Urate exporter , CD antigen CD338

Protein function

High-capacity urate exporter functioning in both renal and extrarenal urate excretion. Plays a role in porphyrin homeostasis as it is able to mediates the export of protoporhyrin IX (PPIX) both from mitochondria to cytosol and from cytosol to extracellular space, and cellular export of hemin, and heme. Xenobiotic transporter that may play an important role in the exclusion of xenobiotics from the brain. Appears to play a major role in the multidrug resistance phenotype of several cancer cell lines. Implicated in the efflux of numerous drugs and xenobiotics: mitoxantrone, the photosensitizer pheophorbide, camptothecin, methotrexate, azidothymidine (AZT), and the anthracyclines daunorubicin and doxorubicin.

Protein tissue specificity

Highly expressed in placenta. Low expression in small intestine, liver and colon.

Protein sequence and domain

The extracellular loop 3 (ECL3) is involved in binding porphyrins and transfer them to other carriers, probably albumin. / Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily. [View classification] / Contains 1 ABC transmembrane type-2 domain. / Contains 1 ABC transporter domain.

Protein post-translational modifications

Glycosylation-deficient ABCG2 is normally expressed and functional.

Protein cellular localization

Cell membrane / Multi-pass membrane protein / Mitochondrion membrane / Multi-pass membrane protein

Research area

All research areas>Transport and Trafficking>ABC
(View all antibody categories related to Transport and Trafficking)

Note

AntibodyPlus can customize ABCG2 Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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Immunofluorescence analysis of Human breast cancer tissue

1: ABCG2 Polyclonal Antibody(red) was diluted at 1:200 (4 degree Celsius,overnight).
2: Cy3 labled Secondary antibody was diluted at 1:300 (room temperature, 50min).
3: Picture B: DAPI(blue) 10min. Picture A:Target. Picture B: DAPI. Picture C: merge of A+B.
 

Immunofluorescence analysis of Human breast cancer tissue

1: ABCG2 Polyclonal Antibody(red) was diluted at 1:200 (4 degree Celsius,overnight).
2: Cy3 labled Secondary antibody was diluted at 1:300 (room temperature, 50min).
3: Picture B: DAPI(blue) 10min. Picture A:Target. Picture B: DAPI. Picture C: merge of A+B.
 

Immunofluorescence analysis of Human lung cancer tissue

1: ABCG2 Polyclonal Antibody(red) was diluted at 1:200 (4 degree Celsius,overnight).
2: Cy3 labled Secondary antibody was diluted at 1:300 (room temperature, 50min).
3: Picture B: DAPI(blue) 10min. Picture A:Target. Picture B: DAPI. Picture C: merge of A+B.
 

Immunofluorescence analysis of Human lung cancer tissue

1: ABCG2 Polyclonal Antibody(red) was diluted at 1:200 (4 degree Celsius,overnight).
2: Cy3 labled Secondary antibody was diluted at 1:300 (room temperature, 50min).
3: Picture B: DAPI(blue) 10min. Picture A:Target. Picture B: DAPI. Picture C: merge of A+B.
 

Immunofluorescence analysis of Human kidney tissue

1: ABCG2 Polyclonal Antibody(red) was diluted at 1:200 (4 degree Celsius,overnight).
2: Cy3 labled Secondary antibody was diluted at 1:300 (room temperature, 50min).
3: Picture B: DAPI(blue) 10min. Picture A:Target. Picture B: DAPI. Picture C: merge of A+B.
 

Immunofluorescence analysis of Human kidney tissue

1: ABCG2 Polyclonal Antibody(red) was diluted at 1:200 (4 degree Celsius,overnight).
2: Cy3 labled Secondary antibody was diluted at 1:300 (room temperature, 50min).
3: Picture B: DAPI(blue) 10min. Picture A:Target. Picture B: DAPI. Picture C: merge of A+B.


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