Rabbit polyclonal ACE antibody (A2805)

$69.00$259.00

Reactivity: Human,Mouse
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

Clear
-$50 as credit for submitting review for primary antibody
Shipping notice:
Product will be delivered in 6 to 8 Business Days

Rabbit polyclonal ACE antibody (A2805)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:500 – 1:2000

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal ACE antibody.

Alternative names:

Check alternative names for the antibody

Expand

DCP antibody, ICH antibody, ACE1 antibody, DCP1 antibody, CD143 antibody, MVCD3 antibody
ACE 1 antibody|ACE antibody|ACE T antibody|ACE_HUMAN antibody|ACE1 antibody|Angiotensin converting enzyme somatic isoform antibody|Angiotensin converting enzyme testis specific isoform antibody|Angiotensin I converting enzyme 1 antibody|Angiotensin I converting enzyme antibody|Angiotensin I converting enzyme peptidyl dipeptidase A 1 antibody|angiotensin I converting enzyme peptidyl-dipeptidase A 1 transcript antibody|Angiotensin-converting enzyme antibody|Carboxycathepsin antibody|CD 143 antibody|CD143 antibody|CD143 antigen antibody|DCP 1 antibody|DCP antibody|DCP1 antibody|Dipeptidyl carboxypeptidase 1 antibody|Dipeptidyl carboxypeptidase I antibody|Kininase II antibody|MGC26566 antibody|MVCD3 antibody|Peptidase P antibody|Peptidyl dipeptidase A antibody|soluble form antibody|Testicular ECA antibody|Anti-Angiotensin Converting Enzyme 1 antibody [9B9] (ab77990)

SCBT cat No: sc-23908|sc-69994|sc-69993|sc-69991|sc-69992|sc-23909|sc-374198|sc-12187|sc-271860|sc-20791|sc-376132|sc-12184|

Name

Rabbit polyclonal ACE antibody

Catalogue No.

A2805

Reactivity

Human, Mouse

Immunogen

Recombinant protein of human ACE

Host

Rabbit

Applications

WB

Recommended dilution

WB 1:500 – 1:2000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 150kDa/Observed: Refer to figures

Formulation

ACE antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

ACE antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

DCP antibody, ICH antibody, ACE1 antibody, DCP1 antibody, CD143 antibody, MVCD3 antibody

Database links

Human UniProt/Swiss-Prot:P12821

Protein names

DCP, ICH, ACE1, DCP1, CD143, MVCD3

Protein function

Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilator. Has also a glycosidase activity which releases GPI-anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety.

Protein tissue specificity

Ubiquitously expressed, with highest levels in lung, kidney, heart, gastrointestinal system and prostate. Isoform Testis-specific is expressed in spermatocytes and adult testis.

Protein sequence and domain

Belongs to the peptidase M2 family.

Protein post-translational modifications

Phosphorylated by CK2 on Ser-1299; which allows membrane retention.

Protein cellular localization

Angiotensin-converting enzyme, soluble form: Secreted.; Cell membrane; Single-pass type I membrane protein. Cytoplasm . Note: Detected in both cell membrane and cytoplasm in neurons.

Background

This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active.

Research area

All research areas>Synthesis and Degradation>ACE
(View all antibody categories related to Synthesis and Degradation)

Note

AntibodyPlus can customize ACE antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

Reviews


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review

There are no reviews for this product yet.
By submitting a review, get following benefits:

1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!

view database submit reviews

There is no extra validation for this product yet.
Check other extra validated antibodies below:



Welcome to AntibodyPlus!