Rabbit Polyclonal Acetyl-Cytokeratin-pan (K194) antibody (STJ90157)

$99.00$319.00

Reactivity: Human, Mouse, Rat
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Acetyl-Cytokeratin-pan (K194) antibody (STJ90157)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-1:2000; ELISA 1:20000;

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Cytokeratin-pan (Acetyl Lys194) Polyclonal Antibody.

Alternative names:

Check alternative names for the antibody

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KRT2 antibody, KRT2A antibody, KRT2E antibody,|CK 2e antibody|Cytokeratin-2e antibody|Epithelial keratin-2e antibody|K2e antibody|Keratin type II cytoskeletal 2 epidermal antibody|Keratin-2 epidermis antibody|KRT2 antibody|KRT2A antibody|KRT2E antibody|Type-II keratin Kb2 antibody|Anti-Cytokeratin 2e antibody [Ks2.342.7.1] (ab19122)
SCBT cat No: sc-58731|sc-49179|

 

Name

Cytokeratin-pan (Acetyl Lys194) Polyclonal Antibody

Catalogue No.

STJ90157

Reactivity

Human, Mouse, Rat

Specificity

Acetyl-Cytokeratin-pan (K194) Polyclonal Antibody detects endogenous levels of Cytokeratin protein only when acetylated at K194.

Immunogen

Synthesized acetyl-peptide derived from human Cytokeratin around the acetylation site of K194

Host

Rabbit

Applications

WB, ELISA

Recommended dilution

WB 1:500-1:2000; ELISA 1:20000;

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

65 kDa

Formulation

Cytokeratin-pan (Acetyl Lys194) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

Cytokeratin-pan (Acetyl Lys194) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Keratin, type II cytoskeletal 2 epidermal antibody, Cytokeratin-2e antibody, CK-2e antibody, Epithelial keratin-2e antibody, Keratin-2 epidermis antibody, Keratin-2e antibody, K2e antibody, Type-II keratin Kb2 antibody

Database links

Human UniProt/Swiss-Prot:P35908 ;Human Entrez Gene: 3849;

Protein names

Keratin, type II cytoskeletal 2 epidermal , Cytokeratin-2e , CK-2e , Epithelial keratin-2e , Keratin-2 epidermis , Keratin-2e , K2e , Type-II keratin Kb2

Protein function

Probably contributes to terminal cornification. Associated with keratinocyte activation, proliferation and keratinization.

Protein tissue specificity

Expressed in the upper spinous and granular suprabasal layers of normal adult epidermal tissues from most body sites including thigh, breast nipple, foot sole, penile shaft and axilla. Not present in foreskin, squamous metaplasias and carcinomas. Expression in hypertrophic and keloid scars begins in the deepest suprabasal layer. Weakly expressed in normal gingiva and tongue, however expression is induced in benign keratoses of lingual mucosa and in mild-to-moderate oral dysplasia with orthokeratinization.

Involvement in disease

Ichthyosis bullosa of Siemens (IBS) [MIM:146800]: A rare autosomal dominant skin disorder displaying a type of epidermolytic hyperkeratosis characterized by generalized erythema and extensive blistering from birth. Large, dark gray hyperkeratoses are observed in later weeks. The skin of IBS patients is unusually fragile and has a tendency to shed the outer layers of the epidermis, producing localized denuded areas (molting effect). IBS usually improves with age so that in most middle-aged patients the hyperkeratosis and keratotic lichenification is limited to the flexural folds of the major joints. . Note: The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the intermediate filament family.

Research area

All research areas>Structural Proteins>Cytokeratin
(View all antibody categories related to Structural Proteins)

Note

AntibodyPlus can customize Cytokeratin-pan (Acetyl Lys194) Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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