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Rabbit Polyclonal Acetyl-Histone H2A (K5) antibody (STJ90117)
Supplier: St John’s Laboratory Ltd.
Recommended applications: IHC, ELISA
Recommended dilution: IHC 1:100-1:300; ELISA 1:5000;
Recommended protocols: check protocols
Click or hover above images to see image description for Acetyl Histone H2A (K5) Polyclonal Antibody.
Check alternative names for the antibodyExpand
H2AFZ antibody, H2AZ antibody,|H2A histone family member Z antibody|H2A.z antibody|H2A/z antibody|H2afz antibody|H2AZ antibody|H2AZ_HUMAN antibody|Histone H2A.Z antibody|MGC117173 antibody|Anti-Histone H2A.Z antibody (ab4174) ChIP Grade
SCBT cat No: sc-67218|
Acetyl Histone H2A (K5) Polyclonal Antibody
|Catalogue No.|| |
Human, Mouse, Rat
Acetyl-Histone H2A (K5) Polyclonal Antibody detects endogenous levels of Histone H2A protein only when acetylated at K5.
Synthesized acetyl-peptide derived from Acetyl Histone H2A (K5) at AA range 1-80
|Recommended dilution|| |
IHC 1:100-1:300; ELISA 1:5000;
|Molecular weight|| |
Acetyl Histone H2A (K5) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Acetyl Histone H2A (K5) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Histone H2A.Z antibody, H2A/z antibody
|Protein names|| |
Histone H2A.Z , H2A/z
|Protein function|| |
Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for chromosome segregation during cell division.
|Protein sequence and domain|| |
Belongs to the histone H2A family.
|Protein post-translational modifications|| |
Monoubiquitination of Lys-122 gives a specific tag for epigenetic transcriptional repression. / Acetylated on Lys-5, Lys-8 and Lys-12 during interphase. Acetylation disappears at mitosis (By similarity). / Monomethylated on Lys-5 and Lys-8 by SETD6. SETD6 predominantly methylates Lys-8, lys-5 being a possible secondary site. / Not phosphorylated.
|Protein cellular localization|| |
Nucleus / Chromosome
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St John’s Laboratory Ltd.
|Product type|| |
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