Rabbit polyclonal ACOX1 antibody (A8091)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal ACOX1 antibody (A8091)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:100 – 1:200

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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ACOX antibody, SCOX antibody, PALMCOX antibody
ACOX antibody|ACOX1 antibody|ACOX1_HUMAN antibody|Acyl CoA oxidase 1 palmitoyl antibody|Acyl CoA oxidase straight chain antibody|AOX antibody|EC 1.3.3.6 antibody|PALMCOX antibody|Palmitoyl CoA oxidase antibody|Palmitoyl-CoA oxidase antibody|Peroxisomal acyl coenzyme A oxidase 1 antibody|Peroxisomal acyl-coenzyme A oxidase 1 antibody|Peroxisomal fatty acyl CoA oxidase antibody|SCOX antibody|Straight chain acyl CoA oxidase antibody|Straight-chain acyl-CoA oxidase antibody|Anti-ACOX1 antibody [EPR19038] (ab184032)

SCBT cat No: sc-130678|sc-107375|sc-107376|sc-98499|

Name

Rabbit polyclonal ACOX1 antibody

Catalogue No.

A8091

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human ACOX1

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:100 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 74kDa/Observed: Refer to figures

Formulation

ACOX1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

ACOX1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

ACOX antibody, SCOX antibody, PALMCOX antibody

Database links

Human UniProt/Swiss-Prot:Q15067

Protein names

ACOX, SCOX, PALMCOX

Protein function

Catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. Isoform 1 shows highest activity against medium-chain fatty acyl-CoAs and activity decreases with increasing chain length. Isoform 2 is active against a much broader range of substrates and shows activity towards very long-chain acyl-CoAs. Isoform 2 is twice as active as isoform 1 against 16-hydroxy-palmitoyl-CoA and is 25% more active against 1,16-hexadecanodioyl-CoA.

Protein tissue specificity

Widely expressed with highest levels of isoform 1 and isoform 2 detected in testis. Isoform 1 is expressed at higher levels than isoform 2 in liver and kidney while isoform 2 levels are higher in brain, lung, muscle, white adipose tissue and testis. Levels are almost equal in heart.

Protein sequence and domain

Belongs to the acyl-CoA oxidase family.

Protein cellular localization

Peroxisome.

Background

The protein encoded by this gene is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids. Alternatively spliced transcript variants encoding different isoforms have been identified.

Note

AntibodyPlus can customize ACOX1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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