Rabbit polyclonal ACTN1 antibody (A1160)


Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal ACTN1 antibody (A1160)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal ACTN1 antibody.

Alternative names:

Check alternative names for the antibody


ACTN1 antibody,FLJ40884 antibody,FLJ54432 antibody
actinin 1 smooth muscle antibody|Actinin alpha 1 antibody|actinin, alpha 1 antibody|ACTN 1 antibody|Actn1 antibody|ACTN1_HUMAN antibody|Alpha Actinin 1 antibody|Alpha actinin cytoskeletal isoform antibody|Alpha-actinin cytoskeletal isoform antibody|Alpha-actinin-1 antibody|BDPLT15 antibody|F actin cross linking protein antibody|F-actin cross-linking protein antibody|FLJ40884 antibody|FLJ54432 antibody|Non muscle alpha actinin 1 antibody|Non-muscle alpha-actinin-1 antibody|Anti-alpha Actinin antibody [0.T.02] (ab18061)

SCBT cat No: sc-7454|sc-17829|sc-15335|sc-7453|


Rabbit polyclonal ACTN1 antibody

Catalogue No.



Human, Mouse, Rat


Recombinant protein of human ACTN1





Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200







Molecular weight

Predicted: 103kDa/Observed: Refer to Figures


ACTN1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.


ACTN1 antibody was purified using affinity purification.


Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

ACTN1 antibody,FLJ40884 antibody,FLJ54432 antibody

Database links

Human UniProt/Swiss-Prot:P12814

Protein names


Protein function

F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein.

Protein sequence and domain

Belongs to the alpha-actinin family.; Contains 1 actin-binding domain.; Contains 2 CH (calponin-homology) domains.; Contains 2 EF-hand domains.; Contains 4 spectrin repeats.

Protein cellular localization

Cytoplasm, cytoskeleton . Cytoplasm, myofibril, sarcomere, Z line . Cell membrane . Cell junction . Cell projection, ruffle . Note: Colocalizes with MYOZ2 and PPP3CA at the Z-line of heart and skeletal muscle. Colocalizes with PSD in membrane ruffles and central reticular structures (By similarity).


alpha-Actinin belongs to the spectrin family of cytoskeletal proteins. It was first recognized as an actin cross-linking protein, forming an antiparallel homodimer with an actin binding head at the amino terminus of each monomer. More recently, alpha-actinin has been shown to interact with a large number of proteins involved in signaling to the cytoskeleton including those involved in cellular adhesion, migration, and immune cell targeting (1). The interaction of alpha-actinin with intercellular adhesion molecule-5 (ICAM-5) helps to promote neurite outgrowth (2). In osteoblasts, interaction of alpha-actinin with integrins stabilizes focal adhesions and may protect cells from apoptosis (3). Isoforms 1 and 4 of alpha-actinin, which are non-muscle isoforms, are present in stress fibers, sites of adhesion and intercellular contacts, filopodia, and lamellipodia. The muscle isoforms 2 and 3 localize to the Z-discs of striated muscle and to dense bodies and plaques in smooth muscle (1).


AntibodyPlus can customize ACTN1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody


ABclonal Inc.


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