Rabbit polyclonal ACY1 antibody (A6351)

$69.00$259.00

Reactivity: Human,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal ACY1 antibody (A6351)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:10 – 1:100

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

Expand

ACY-1 antibody, ACY1D antibody, HEL-S-5 antibody
ACY 1 antibody|ACY-1 antibody|Acy1 antibody|ACY1_HUMAN antibody|ACY1D antibody|ACYLASE antibody|Acylase I antibody|Aminoacylase-1 antibody|EC 3.5.1.14 antibody|epididymis secretory protein Li 5 antibody|HEL-S-5 antibody|N acyl L amino acid amidohydrolase antibody|N-acyl-L-amino-acid amidohydrolase antibody|OTTHUMP00000212459 antibody|OTTHUMP00000212462 antibody|OTTHUMP00000212463 antibody|OTTHUMP00000212464 antibody|OTTHUMP00000212465 antibody|Anti-Aminoacylase 1 antibody (ab54960)

SCBT cat No: sc-271705|sc-271019|sc-374298|

Name

Rabbit polyclonal ACY1 antibody

Catalogue No.

A6351

Reactivity

Human, Rat

Immunogen

Recombinant protein of human ACY1

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:10 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 45kDa/Observed: Refer to Figures

Formulation

ACY1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

ACY1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

ACY-1 antibody, ACY1D antibody, HEL-S-5 antibody

Database links

Human UniProt/Swiss-Prot:Q03154

Protein names

ACY-1, ACY1D, HEL-S-5

Protein function

Involved in the hydrolysis of N-acylated or N-acetylated amino acids (except L-aspartate).

Protein tissue specificity

Expression is highest in kidney, strong in brain and weaker in placenta and spleen.

Protein sequence and domain

Belongs to the peptidase M20A family.

Protein cellular localization

Cytoplasm.

Background

This gene encodes a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and an acyl group, and has been postulated to function in the catabolism and salvage of acylated amino acids. This gene is located on chromosome 3p21.1, a region reduced to homozygosity in small-cell lung cancer (SCLC), and its expression has been reported to be reduced or undetectable in SCLC cell lines and tumors. The amino acid sequence of human aminoacylase-1 is highly homologous to the porcine counterpart, and this enzyme is the first member of a new family of zinc-binding enzymes. Mutations in this gene cause aminoacylase-1 deficiency, a metabolic disorder characterized by central nervous system defects and increased urinary excretion of N-acetylated amino acids. Alternative splicing of this gene results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ABHD14A (abhydrolase domain containing 14A) gene, as represented in GeneID:100526760. A related pseudogene has been identified on chromosome 18.

Note

AntibodyPlus can customize ACY1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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