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Rabbit polyclonal ADA antibody (A1019)
Supplier: ABclonal Inc.
Recommended applications: WB,IHC,IF
WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit polyclonal ADA antibody.
Check alternative names for the antibodyExpand
ADA1 antibody, ADA antibody
ada antibody|ADA_HUMAN antibody|ADA1 antibody|Adenosine aminohydrolase antibody|Adenosine deaminase antibody|Anti-ADA antibody (ab175310)
SCBT cat No: sc-7450|sc-376889|sc-28346|sc-25747|sc-7451|
Rabbit polyclonal ADA antibody
|Catalogue No.|| |
Human, Mouse, Rat
Recombinant protein of human ADA
WB, IHC, IF
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
Predicted: 41kDa/Observed: Refer to Figures
ADA antibody was tube-contained.
ADA antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Alternative antibody names|| |
ADA1 antibody, ADA antibody
|Database links|| |
|Protein names|| |
|Protein function|| |
Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. Acts as a positive regulator of T-cell coactivation, by binding DPP4. Its interaction with DPP4 regulates lymphocyte-epithelial cell adhesion.
|Protein tissue specificity|| |
Found in all tissues, occurs in large amounts in T-lymphocytes and, at the time of weaning, in gastrointestinal tissues.
|Protein sequence and domain|| |
Belongs to the adenosine and AMP deaminases family.
|Protein cellular localization|| |
Cell membrane; Peripheral membrane protein; Extracellular side. Cell junction. Cytoplasmic vesicle lumen . Cytoplasm . Note: Colocalized with DPP4 at the cell junction in lymphocyte-epithelial cell adhesion.
This gene encodes an enzyme that catalyzes the hydrolysis of adenosine to inosine. Various mutations have been described for this gene and have been linked to human diseases. Deficiency in this enzyme causes a form of severe combined immunodeficiency disease (SCID), in which there is dysfunction of both B and T lymphocytes with impaired cellular immunity and decreased production of immunoglobulins, whereas elevated levels of this enzyme have been associated with congenital hemolytic anemia. [provided by RefSeq, Jul 2008]
AntibodyPlus can customize ADA antibody according to your requirement, including bulk product size,etc. Please contact firstname.lastname@example.org. AntibodyPlus provides antibody trial sample for your own antibody validation.
|Product type|| |
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