Rabbit polyclonal ADRA1A antibody (A1471)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

Clear
-$50 as credit for submitting review for primary antibody
Shipping notice:
Product will be delivered in 6 to 8 Business Days

Rabbit polyclonal ADRA1A antibody (A1471)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:500 – 1:2000

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal ADRA1A antibody.

Alternative names:

Check alternative names for the antibody

Expand

ADRA1C antibody, ADRA1L1 antibody, ALPHA1AAR antibody
ADA1A_HUMAN antibody|ADRA1A antibody|Adra1c antibody|ADRA1L1 antibody|Adrenergic alpha1A receptor antibody|Adrenergic alpha1C receptor antibody|Adrenergic receptor alpha 1a antibody|Adrenergic receptor alpha 1c antibody|Adrenergic, alpha 1A , receptor variant 1 antibody|Adrenergic, alpha 1A , receptor variant 11 antibody|Adrenergic, alpha 1A , receptor variant 3 antibody|Adrenergic, alpha 1A , receptor variant 5 antibody|Adrenergic, alpha 1A , receptor variant 8 antibody|Adrenoceptor alpha 1A antibody|Alpha 1A adrenoreceptor antibody|Alpha 1C adrenergic receptor antibody|Alpha-1A adrenergic receptor antibody|Alpha-1A adrenoceptor antibody|Alpha-1A adrenoreceptor antibody|Alpha-1C adrenergic receptor antibody|Alpha-adrenergic receptor 1c antibody|Alpha1A adrenergic receptor antibody|ALPHA1AAR antibody|G protein coupled receptor antibody|Anti-alpha 1a Adrenergic Receptor antibody [EPR9691(B)] (ab137123)

SCBT cat No: sc-100291|sc-1477|sc-31358|sc-28982|

Name

Rabbit polyclonal ADRA1A antibody

Catalogue No.

A1471

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human ADRA1A

Host

Rabbit

Applications

WB

Recommended dilution

WB 1:500 – 1:2000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 52kDa/Observed: Refer to Figures

Formulation

ADRA1A antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

ADRA1A antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

ADRA1C antibody, ADRA1L1 antibody, ALPHA1AAR antibody

Database links

Human UniProt/Swiss-Prot:P35348

Protein names

ADRA1C, ADRA1L1, ALPHA1AAR

Protein function

This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine(PE)-stimulated ERK signaling in cardiac myocytes.

Protein tissue specificity

Expressed in heart, brain, liver and prostate, but not in kidney, lung, adrenal, aorta and pituitary. Within the prostate, expressed in the apex, base, periurethral and lateral lobe. Isoform 4 is the most abundant isoform expressed in the prostate with high levels also detected in liver and heart.

Protein sequence and domain

Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRA1A sub-subfamily.

Protein post-translational modifications

C-terminal Ser or Thr residues may be phosphorylated.

Protein cellular localization

Nucleus membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Note: Location at the nuclear membrane facilitates heterooligomerization and regulates ERK-mediated signaling in cardiac myocytes. Colocalizes with GNAQ, PLCB1 as well as LAP2 at the nuclear membrane of cardiac myocytes.

Background

ADRA1A, also named as ADRA1C, belongs to the G-protein coupled receptor 1 family. ADRA1A mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. The antibody is specific to ADRA1A.

Research area

All research areas>Membrane Receptors>AR
(View all antibody categories related to Membrane Receptors)

Note

AntibodyPlus can customize ADRA1A antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

Reviews


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review

There are no reviews for this product yet.
By submitting a review, get following benefits:

1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!

view database submit reviews

There is no extra validation for this product yet.
Check other extra validated antibodies below:



Welcome to AntibodyPlus!