Rabbit polyclonal ADRA2A antibody (A2809)

$69.00$259.00

Reactivity: Human,Mouse
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal ADRA2A antibody (A2809)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:500 – 1:2000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

Expand

ADRA2 antibody, ADRAR antibody, ZNF32 antibody, ADRA2R antibody, ALPHA2AAR antibody
ADA2A_HUMAN antibody|ADRA2 antibody|ADRA2A antibody|ADRA2R antibody|ADRAR antibody|Adrenergic alpha 2A receptor antibody|Alpha 2 adrenergic receptor subtype C10 antibody|Alpha 2A adrenergic receptor antibody|Alpha 2AAR subtype C10 antibody|Alpha-2 adrenergic receptor subtype C10 antibody|alpha-2-adrenergic receptor, platelet type antibody|Alpha-2A adrenergic receptor antibody|Alpha-2A adrenoceptor antibody|Alpha-2A adrenoreceptor antibody|Alpha-2AAR antibody|ALPHA2AAR antibody|OTTHUMP00000058849 antibody|ZNF32 antibody|Anti-alpha 2a Adrenergic Receptor antibody (ab85570)

SCBT cat No: sc-1478|sc-31356|sc-28983|sc-31357|

Name

Rabbit polyclonal ADRA2A antibody

Catalogue No.

A2809

Reactivity

Human, Mouse

Immunogen

Recombinant protein of human ADRA2A

Host

Rabbit

Applications

WB

Recommended dilution

WB 1:500 – 1:2000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 49kDa/Observed: Refer to figures

Formulation

ADRA2A antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

ADRA2A antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

ADRA2 antibody, ADRAR antibody, ZNF32 antibody, ADRA2R antibody, ALPHA2AAR antibody

Database links

Human UniProt/Swiss-Prot:P08913

Protein names

ADRA2, ADRAR, ZNF32, ADRA2R, ALPHA2AAR

Protein function

Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is oxymetazoline > clonidine > epinephrine > norepinephrine > phenylephrine > dopamine > p-synephrine > p-tyramine > serotonin = p-octopamine. For antagonists, the rank order is yohimbine > phentolamine = mianserine > chlorpromazine = spiperone = prazosin > propanolol > alprenolol = pindolol.

Protein sequence and domain

Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRA2A sub-subfamily.

Protein cellular localization

Cell membrane ; Multi-pass membrane protein .

Background

Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Studies in mouse revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons; the alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes alpha2A subtype and it contains no introns in either its coding or untranslated sequences.

Research area

All research areas>Membrane Receptors>AR
(View all antibody categories related to Membrane Receptors)

Note

AntibodyPlus can customize ADRA2A antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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