Rabbit polyclonal AHCY antibody (A5300)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal AHCY antibody (A5300)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

Expand

SAHH antibody, adoHcyase antibody
Adenosylhomocysteinase antibody|AdoHcyase antibody|ahcY antibody|S adenosyl L homocysteine hydrolase antibody|S adenosylhomocysteine hydrolase antibody|S-adenosyl-L-homocysteine hydrolase antibody|SAHH antibody|SAHH_HUMAN antibody|Anti-S adenosylhomocysteine hydrolase antibody – N-terminal (ab170285)

SCBT cat No: sc-271389|sc-393129|sc-365070|sc-292967|sc-55758|sc-55759|

Name

Rabbit polyclonal AHCY antibody

Catalogue No.

A5300

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human AHCY

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 48kDa/Observed: Refer to Figures

Formulation

AHCY antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

AHCY antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

SAHH antibody, adoHcyase antibody

Database links

Human UniProt/Swiss-Prot:P23526

Protein names

SAHH, adoHcyase

Protein function

Adenosylhomocysteine is a competitive inhibitor of S-adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in the control of methylations via regulation of the intracellular concentration of adenosylhomocysteine.

Protein sequence and domain

Belongs to the adenosylhomocysteinase family.

Protein cellular localization

Cytoplasm . Melanosome . Note: Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

Background

S-adenosylhomocysteine hydrolase belongs to the adenosylhomocysteinase family. It catalyzes the reversible hydrolysis of S-adenosylhomocysteine (AdoHcy) to adenosine (Ado) and L-homocysteine (Hcy). Thus, it regulates the intracellular S-adenosylhomocysteine (SAH) concentration thought to be important for transmethylation reactions. Deficiency in this protein is one of the different causes of hypermethioninemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Note

AntibodyPlus can customize AHCY antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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